Results 11 to 20 of about 1,352,832 (329)

Polysomally Protected Viruses [PDF]

open access: yesPhys. Biol. 18 046009 (2021), 2021
It is conceivable that an RNA virus could use a polysome, that is, a string of ribosomes covering the RNA strand, to protect the genetic material from degradation inside a host cell. This paper discusses how such a virus might operate, and how its presence might be detected by ribosome profiling.
arxiv   +1 more source

Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. [PDF]

open access: yesPLoS ONE, 2014
Intact RNA from exosomes/microvesicles (collectively referred to as microvesicles) has sparked much interest as potential biomarkers for the non-invasive analysis of disease.
Kevin C Miranda   +8 more
doaj   +1 more source

Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA

open access: yesCells, 2020
Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic ...
Ivan Laptev, Olga Dontsova, Petr Sergiev
doaj   +1 more source

Growth-laws and invariants from ribosome biogenesis in lower Eukarya [PDF]

open access: yesPhys. Rev. Research 3, 013020 (2021), 2020
Eukarya and Bacteria are the most evolutionarily distant domains of life, which is reflected by differences in their cellular structure and physiology. For example, Eukarya feature membrane-bound organelles such as nuclei and mitochondria, whereas Bacteria have none.
arxiv   +1 more source

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

open access: yesNucleic Acids Res., 2012
SILVA (from Latin silva, forest, http://www.arb-silva.de) is a comprehensive web resource for up to date, quality-controlled databases of aligned ribosomal RNA (rRNA) gene sequences from the Bacteria, Archaea and Eukaryota domains and supplementary ...
Christian Quast   +7 more
semanticscholar   +1 more source

The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted

open access: yesFrontiers in Microbiology, 2020
Synthesis and assembly of ribosomal components are fundamental cellular processes and generally well-conserved within the main groups of organisms. Yet, provocative variations to the general schemes exist. We have discovered an unusual processing pathway
Ulf Birkedal   +4 more
doaj   +1 more source

Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome

open access: yesScience, 2020
Shifting frames to make more proteins Severe acute respiratory syndrome coronavirus 2 critically depends on the ribosomal frameshifting that occurs between two large open reading frames in its genomic RNA for expression of viral replicase.
P. R. Bhatt   +13 more
semanticscholar   +1 more source

Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies

open access: yesNucleic Acids Research, 2012
16S ribosomal RNA gene (rDNA) amplicon analysis remains the standard approach for the cultivation-independent investigation of microbial diversity. The accuracy of these analyses depends strongly on the choice of primers.
A. Klindworth   +6 more
semanticscholar   +1 more source

The European ribosomal RNA database [PDF]

open access: yesNucleic Acids Research, 2004
The European ribosomal RNA database aims to compile all complete or nearly complete ribosomal RNA sequences from both the small (SSU) and large (LSU) ribosomal subunits. All sequences are available in aligned format. Sequence alignment is based on the secondary structure of the molecules, as determined by comparative sequence analysis.
Wuyts, Jan   +2 more
openaire   +5 more sources

Autophagy regulates rRNA synthesis

open access: yesNucleus, 2022
Autophagy has emerged as a key regulator of cell metabolism. Recently, we have demonstrated that autophagy is involved in RNA metabolism by regulating ribosomal RNA (rRNA) synthesis.
Yinfeng Xu, Wei Wan
doaj   +1 more source

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