Results 11 to 20 of about 312,612 (262)

Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA

open access: yesCells, 2020
Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic ...
Ivan Laptev, Olga Dontsova, Petr Sergiev
doaj   +1 more source

Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. [PDF]

open access: yesPLoS ONE, 2014
Intact RNA from exosomes/microvesicles (collectively referred to as microvesicles) has sparked much interest as potential biomarkers for the non-invasive analysis of disease.
Kevin C Miranda   +8 more
doaj   +1 more source

The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted

open access: yesFrontiers in Microbiology, 2020
Synthesis and assembly of ribosomal components are fundamental cellular processes and generally well-conserved within the main groups of organisms. Yet, provocative variations to the general schemes exist. We have discovered an unusual processing pathway
Ulf Birkedal   +4 more
doaj   +1 more source

Autophagy regulates rRNA synthesis

open access: yesNucleus, 2022
Autophagy has emerged as a key regulator of cell metabolism. Recently, we have demonstrated that autophagy is involved in RNA metabolism by regulating ribosomal RNA (rRNA) synthesis.
Yinfeng Xu, Wei Wan
doaj   +1 more source

Conformational switches control early maturation of the eukaryotic small ribosomal subunit

open access: yeseLife, 2019
Eukaryotic ribosome biogenesis is initiated with the transcription of pre-ribosomal RNA at the 5’ external transcribed spacer, which directs the early association of assembly factors but is absent from the mature ribosome.
Mirjam Hunziker   +5 more
doaj   +1 more source

The complete chloroplast genome of Juniperus squamata (Cupressaceae), a shrubby conifer from Asian Mountains

open access: yesMitochondrial DNA. Part B. Resources, 2019
The complete chloroplast genome of Juniperus squamata, a shrubby conifer of ornamental value, is determined in this study. The complete chloroplast genome size is 127,792 bp in length.
Siyu Xie   +4 more
doaj   +1 more source

FIERY1 promotes microRNA accumulation by suppressing rRNA-derived small interfering RNAs in Arabidopsis

open access: yesNature Communications, 2019
Arabidopsis AGO1 binds both microRNA (miRNA) and endogenous small interfering RNA (siRNA). Here the authors show that 5′−3′ RNA degradation suppresses siRNA biogenesis from ribosomal RNA to prevent overloading of AGO1 with ribosomal siRNA and maintain ...
Chenjiang You   +8 more
doaj   +1 more source

Recent Advances on the Structure and Function of RNA Acetyltransferase Kre33/NAT10

open access: yesCells, 2019
Ribosome biogenesis is one of the most energy demanding processes in the cell. In eukaryotes, the main steps of this process occur in the nucleolus and include pre-ribosomal RNA (pre-rRNA) processing, post-transcriptional modifications, and assembly of ...
Sophie Sleiman, Francois Dragon
doaj   +1 more source

Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer

open access: yesCell Reports, 2020
Summary: The ribosome is an RNA-protein complex that is essential for translation in all domains of life. The structural and catalytic core of the ribosome is its ribosomal RNA (rRNA).
Artem Babaian   +10 more
doaj   +1 more source

Protocol dependence of sequencing-based gene expression measurements. [PDF]

open access: yesPLoS ONE, 2011
RNA Seq provides unparalleled levels of information about the transcriptome including precise expression levels over a wide dynamic range. It is essential to understand how technical variation impacts the quality and interpretability of results, how ...
Tal Raz   +5 more
doaj   +1 more source

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