Results 31 to 40 of about 484,088 (306)

Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes [PDF]

open access: yes, 2016
Saccharomyces cerevisiae sir2Δ or top1Δ mutants exhibit similar phenotypes involving ribosomal DNA, including (i) loss of transcriptional silencing, resulting in non-coding RNA hyperproduction from cryptic RNA polymerase II promoters; (ii) alterations ...
Bjornsti, Mary Ann   +6 more
core   +1 more source

Ribosomal RNA, the lens into life [PDF]

open access: yesRNA, 2015
Our world is, to a first approximation, a microbial world—even our own lives are evolutionarily and molecularly linked to that which we cannot see. This “invisible” world contains nearly unfathomable molecular and genetic diversity. Throughout the 20th century, a metaphor of “war against disease” prevailed: Microbes were hunted under the guise of ...
Daniel McDonald   +3 more
openaire   +3 more sources

RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability

open access: yesRNA Biology
Transcription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand   +7 more
doaj   +1 more source

Ribosomal history reveals origins of modern protein synthesis. [PDF]

open access: yesPLoS ONE, 2012
The origin and evolution of the ribosome is central to our understanding of the cellular world. Most hypotheses posit that the ribosome originated in the peptidyl transferase center of the large ribosomal subunit.
Ajith Harish, Gustavo Caetano-Anollés
doaj   +1 more source

Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe. [PDF]

open access: yes, 2017
Comprehensive understanding of the structure-function relationship of RNA both in real time and at atomic level will have a profound impact in advancing our understanding of RNA functions in biology.
Boerneke, Mark A   +3 more
core   +1 more source

Dynamic relationships between ribosomal conformational and RNA positional changes during ribosomal translocation

open access: yesHeliyon, 2016
Ribosomal translocation catalyzed by EF-G hydrolyzing GTP entails multiple conformational changes of ribosome and positional changes of tRNAs and mRNA in the ribosome.
Ping Xie
doaj   +1 more source

Three Ribosomal Operons of Escherichia coli Contain Genes Encoding Small RNAs That Interact With Hfq and CsrA in vitro

open access: yesFrontiers in Microbiology, 2021
Three out of the seven ribosomal RNA operons in Escherichia coli end in dual terminator structures. Between the two terminators of each operon is a short sequence that we report here to be an sRNA gene, transcribed as part of the ribosomal RNA primary ...
Thomas Søndergaard Stenum   +5 more
doaj   +1 more source

Protocol for Metatranscriptomic analysis of Intestinal Microbiota [PDF]

open access: yes, 2012
The objective of this publication is to provide the detailed protocol for metartancriptomisc studies of animal intestinal microbiota. The protocol describes isolation of high quality microbial community RNA from the mammalian intestinal content ...
Alvaro Hernandez   +4 more
core   +2 more sources

Selection of Peptides Targeting Helix 31 of Bacterial 16S Ribosomal RNA by Screening M13 Phage-Display Libraries

open access: yesMolecules, 2011
Ribosomal RNA is the catalytic portion of ribosomes, and undergoes a variety of conformational changes during translation. Structural changes in ribosomal RNA can be facilitated by the presence of modified nucleotides. Helix 31 of bacterial 16S ribosomal
Christine S. Chow   +4 more
doaj   +1 more source

RNA:protein ratio of the unicellular organism as a characteristic of phosphorous and nitrogen stoichiometry and of the cellular requirement of ribosomes for protein synthesis [PDF]

open access: yes, 2006
Background Mean phosphorous:nitrogen (P:N) ratios and relationships of P:N ratios with the growth rate of organisms indicate a surprising similarity among and within microbial species, plants, and insect herbivores.
A Mehra   +48 more
core   +4 more sources

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