Results 31 to 40 of about 1,606,029 (335)

Recent Advances on the Structure and Function of RNA Acetyltransferase Kre33/NAT10

open access: yesCells, 2019
Ribosome biogenesis is one of the most energy demanding processes in the cell. In eukaryotes, the main steps of this process occur in the nucleolus and include pre-ribosomal RNA (pre-rRNA) processing, post-transcriptional modifications, and assembly of ...
Sophie Sleiman, Francois Dragon
doaj   +1 more source

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA [PDF]

open access: yes, 2012
Ribosomal RNA undergoes various modifications to optimize ribosomal structure and expand the topological potential of RNA. The most common nucleotide modifications in ribosomal RNA (rRNA) are pseudouridylations and 2'-O methylations (Nm), performed by H ...
Entian, Karl-Dieter   +5 more
core   +1 more source

Identification of planorbids from Venezuela by polymerase chain reaction amplification and restriction fragment length polymorphism of internal transcriber spacer of the RNA ribosomal gene.

open access: yesMemórias do Instituto Oswaldo Cruz, 2000
Snails of the genus Biomphalaria from Venezuela were subjected to morphological assessment as well as polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis.
R. Caldeira   +4 more
semanticscholar   +1 more source

Protocol dependence of sequencing-based gene expression measurements. [PDF]

open access: yesPLoS ONE, 2011
RNA Seq provides unparalleled levels of information about the transcriptome including precise expression levels over a wide dynamic range. It is essential to understand how technical variation impacts the quality and interpretability of results, how ...
Tal Raz   +5 more
doaj   +1 more source

Ribosomal history reveals origins of modern protein synthesis. [PDF]

open access: yesPLoS ONE, 2012
The origin and evolution of the ribosome is central to our understanding of the cellular world. Most hypotheses posit that the ribosome originated in the peptidyl transferase center of the large ribosomal subunit.
Ajith Harish, Gustavo Caetano-Anollés
doaj   +1 more source

The European ribosomal RNA database [PDF]

open access: yesNucleic Acids Research, 2004
The European ribosomal RNA database aims to compile all complete or nearly complete ribosomal RNA sequences from both the small (SSU) and large (LSU) ribosomal subunits. All sequences are available in aligned format. Sequence alignment is based on the secondary structure of the molecules, as determined by comparative sequence analysis.
Wuyts, Jan   +2 more
openaire   +3 more sources

Protocol for Metatranscriptomic analysis of Intestinal Microbiota [PDF]

open access: yes, 2012
The objective of this publication is to provide the detailed protocol for metartancriptomisc studies of animal intestinal microbiota. The protocol describes isolation of high quality microbial community RNA from the mammalian intestinal content ...
Alvaro Hernandez   +4 more
core   +2 more sources

Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction

open access: yesBMC Genomics, 2018
Background Ribosomal RNA (rRNA) comprises at least 90% of total RNA extracted from mammalian tissue or cell line samples. Informative transcriptional profiling using massively parallel sequencing technologies requires either enrichment of mature poly ...
Zachary T. Herbert   +20 more
doaj   +1 more source

Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer

open access: yesCell Reports, 2020
Summary: The ribosome is an RNA-protein complex that is essential for translation in all domains of life. The structural and catalytic core of the ribosome is its ribosomal RNA (rRNA).
Artem Babaian   +10 more
doaj   +1 more source

Ribosomal RNA, the lens into life [PDF]

open access: yesRNA, 2015
Our world is, to a first approximation, a microbial world—even our own lives are evolutionarily and molecularly linked to that which we cannot see. This “invisible” world contains nearly unfathomable molecular and genetic diversity. Throughout the 20th century, a metaphor of “war against disease” prevailed: Microbes were hunted under the guise of ...
Daniel McDonald   +3 more
openaire   +3 more sources

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