Results 161 to 170 of about 416,109 (272)

Investigating the Potential for Label‐Free Detection of Cell Apoptosis through Terahertz Nano‐Metasurfaces

Advanced Photonics Research, EarlyView.
This study demonstrates a label‐free optical method to monitor cells using a terahertz metasurface‐based biosensing platform. The obtained terahertz signal change for the cell‐contained nanoslots before and after external stimulus is analyzed in terms of transmittance and frequency shift, dynamically representing the cell apoptosis process.
Yeeun Roh, Jisung Kwak, Sang Jun Sim, Hyun Seok Song, Minah Seo   +4 more
wiley   +1 more source

Development of small interfering RNA delivery system using PEI-PEG-APRPG polymer for antiangiogenic vascular endothelial growth factor tumor-targeted therapy

International Journal of Nanomedicine, 2011
Zong-Xia Lu1, Li-Ting Liu1,2, Xian-Rong Qi11Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, People's Republic of China; 2Department of Pharmacy, School and Hospital of Stomatology, Peking University ...
Lu ZX, Liu LT, Qi XR
doaj  

ROS‐Driven Nanoventilator for MRSA‐Induced Acute Lung Injury Treatment via In Situ Oxygen Supply, Anti‐Inflammation and Immunomodulation

Advanced Science, EarlyView.
A ROS‐driven in situ oxygen supply nanoventilator based on enzyme nanocapsule can convert ROS into O2 through enzyme cascade reaction between SOD and CAT to relieve lung hypoxia, and kill MRSA by releasing vancomycin, which effectively reduces HIF‐1α expression and balances pro‐inflammatory/anti‐inflammatory macrophages ratio, thereby reducing the ...
Zheng Luo, Qi Wang, Xiaotong Fan, Xue Qi Koh, Xian Jun Loh, Caisheng Wu, Zibiao Li, Yun‐Long Wu   +7 more
wiley   +1 more source

Targeting lipoprotein(a): Pharmacotherapy in focus. [PDF]

Eur Heart J Cardiovasc Pharmacother
Tan DS, Ooi ZH, Lew CSF.
europepmc   +1 more source

Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells

Advanced Science, EarlyView.
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang, Jane Frederick, Karla Isabel Medina, Elizabeth Thomas Bartom, Luay Matthew Almassalha, Yaqi Zhang, Greta Wodarcyk, Hao Huang, I Chae Ye, Ruyi Gong, Cody Levi Dunton, Alex Duval, Paola Carrillo Gonzalez, Joshua Pritchard, John Carinato, Iuliia Topchu, Junzui Li, Zhe Ji, Mazhar Adli, Vadim Backman, Daniela Matei   +20 more
wiley   +1 more source

Circular RNA contributes to gastric cancer by targeting Wnt family member 2B as a competing endogenous RNA. [PDF]

World J Gastroenterol
Bai W, Guo ZL, Guo JH, Li F, Bu P, Liu J.   +5 more
europepmc   +1 more source

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

Advanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding, Siwei Mao, Han Wu, Sijia Fang, Ni Zhen, Tianshu Chen, Jiabei Zhu, Xiaochen Tang, Xiaoyang Wang, Fenyong Sun, Guoqing Zhu, Qiuhui Pan, Ji Ma   +12 more
wiley   +1 more source

Erratum: [Corrigendum] lncRNA SNHG3 acts as oncogene in ovarian cancer through miR‑139‑5p and Notch1. [PDF]

Oncol Lett
Zhang L, Li G, Wang X, Zhang Y, Huang X, Wu H.   +5 more
europepmc   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
wiley   +1 more source

The PAZ domain of <i>Aedes aegypti</i> Dicer 2 is critical for accurate and high-fidelity size determination of virus-derived small interfering RNAs. [PDF]

RNA
Reuter M, Parry RH, McFarlane M, Gestuveo RJ, Arif R, Khromykh AA, Brennan B, Varjak M, Castello A, Redecke L, Schnettler E, Kohl A.   +11 more
europepmc   +1 more source