Results 71 to 80 of about 547,696 (232)

The promise and progress of RNA-interference-based antiviral therapy for respiratory syncytial virus.

open access: yesЖурнал инфектологии, 2014
Respiratory syncytial virus (RSV) is a major cause of morbidity in infants, young children, and the elderly worldwide. Presently, there are no explicit recommendations for RSV treatment apart from supportive care.
V. V. Vysochinskayа   +5 more
doaj   +1 more source

cd26 Knockdown Negatively Affects Porcine Parthenogenetic Preimplantation Embryo Development

open access: yesAnimals, 2022
cd26 is ubiquitously distributed in the body, particularly in the endothelial and epithelial cells, with the highest expression in the kidney, liver, and small intestine. In humans, cd26 serves as a marker for the embryo implantation phase.
In-Sul Hwang   +4 more
doaj   +1 more source

Iron oxide nanoparticles and derivatives for biomedical imaging and application in cancer diagnosis and siRNA therapy [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011)   +2 more
core  

RNA Viruses: RNA Roles in Pathogenesis, Coreplication and Viral Load. [PDF]

open access: yes, 2015
The review intends to present and recapitulate the current knowledge on the roles and importance of regulatory RNAs, such as microRNAs and small interfering RNAs, RNA binding proteins and enzymes processing RNAs or activated by RNAs, in cells infected by
Massimo Mallardo,   +2 more
core   +1 more source

Inhibition of Junín virus replication by small interfering RNAs

open access: yesAntiviral Research, 2009
Junín virus (JUNV), the etiological agent of the Argentine hemorrhagic fever, has a single-stranded RNA genome with ambisense expression which encodes for five proteins. In previous works we have demonstrated that the Z arenavirus matrix protein represents an attractive target for antiviral therapy.
Artuso, MC   +4 more
openaire   +5 more sources

Transfer of small interfering RNA by electropermeabilization in tumor spheroids

open access: yesBioelectrochemistry, 2021
The ability to modulate deregulated genes by RNAi provides treatment perspectives in certain diseases including cancers. Electrotransfer of oligonucleotides was studied in vitro, showing a direct transfer of negatively charged siRNA across the plasma membrane into the cytoplasm.
Pelofy, Sandrine   +4 more
openaire   +4 more sources

psRNATarget: a plant small RNA target analysis server (2017 release)

open access: yesNucleic Acids Res., 2018
Plant regulatory small RNAs (sRNAs), which include most microRNAs (miRNAs) and a subset of small interfering RNAs (siRNAs), such as the phased siRNAs (phasiRNAs), play important roles in regulating gene expression.
X. Dai, Zhaohong Zhuang, P. Zhao
semanticscholar   +1 more source

Colored petri net modeling of small interfering RNA-mediated messenger RNA degradation

open access: yesAdvanced Biomedical Research, 2016
Background: Mathematical modeling of biological systems is an attractive way for studying complex biological systems and their behaviors. Petri Nets, due to their ability to model systems with various levels of qualitative information, have been wildly ...
Niloofar Nickaeen   +3 more
doaj   +1 more source

Prevention of Tendon Adhesions by ERK2 Small Interfering RNAs [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Tendon adhesions are one of the most concerning complications after surgical repair of flexor tendon injury. Extracellular signal-regulated kinase (ERK) 2 plays crucial roles in fibroblast proliferation and collagen expression which contributes to the formation of tendon adhesions after flexor tendon surgery. Using a chicken model, we have examined the
Shen Liu   +4 more
openaire   +3 more sources

Nanodiamond as a vector for siRNA delivery to Ewing sarcoma cells

open access: yes, 2011
We investigated the ability of diamond nanoparticles (nanodiamonds, NDs) to deliver small interfering RNA (siRNA) in Ewing sarcoma cells, in the perspective of in vivo anti-cancer nucleic acid drug delivery.
Barnard   +47 more
core   +3 more sources

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