Results 141 to 149 of about 498,663 (149)
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Specific small nuclear RNAs are associated with yeast spliceosomes
Cell, 1986Two different methods have been devised for the analysis and purification of spliceosomes formed in a yeast in vitro splicing system. The first method relies on the electrophoretic separation of ribonucleoprotein particles in composite acrylamide-agarose gels. A large fraction of added substrate is located in spliceosomes, the formation of which can be
Michael Rosbash, Claudio W. Pikielny
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Intracellular transport of microinjected 5S and small nuclear RNAs
Nature, 1982The mechanism by which some RNAs are segregated in the cell nucleus was analysed by microinjecting 32 P-labelled total RNA from HeLa cells into the cytoplasm of Xenopus oocytes. Small nuclear RNAs (u1, U2, U4, U5 and U6) migrated into the cell nucleus, where they became 30-60 fold more concentrated than in the cytoplasm. Other RNAs, such as tRNA and 7S
R. F. Parisot +2 more
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The Genes and Transcription of the Major Small Nuclear RNAs
1988Several unusual features distinguish snRNA genes and make snRNA synthesis an important and interesting subject for study. Although the snRNA genes are very efficiently and accurately transcribed by transcription complexes which use RNA polymerase II (or III, in the case of U6 genes), these genes contain transcription signals that differ from those ...
James E. Dahlberg, Elsebet Lund
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Finding functions for small nuclear RNAs in yeast
Trends in Biochemical Sciences, 1986Abstract Small nuclear RNAs (snRNAs) have been suggested to mediate a variety of steps in gene expression, with an emphasis on essential RNA processing reactions. By using the yeast Saccharomyces cerevisiae , in which genetic and biochemical approaches can be coupled, it is now apparent that the ways in which snRNAs contribute to the growth of even a
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Role for small nuclear RNAs in “programming” chromosomal information?
Nature, 1976ALTHOUGH small nuclear RNAs (snRNAs) have been studied extensively1,2, almost nothing is known about how they function in cells. I present here the results of a detailed study of the behaviour of snRNAs during mitosis, which has uncovered what may be the first important clue as to their function.
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Small nuclear RNA-protein complexes
Biochemical Society Transactions, 1988Iain W. Mattaj, D. Scherly, Jörg Hamm
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Messenger RNA splicing: Role of small nuclear RNA-protein complexes
Advances in Biophysics, 1986Kazuta Takemura +4 more
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