Results 31 to 40 of about 402,636 (258)

Smuggling on the Nanoscale—Fusogenic Liposomes Enable Efficient RNA-Transfer with Negligible Immune Response In Vitro and In Vivo

open access: yesPharmaceutics, 2023
The efficient and biocompatible transfer of nucleic acids into mammalian cells for research applications or medical purposes is a long-standing, challenging task.
Marco Hoffmann   +13 more
doaj   +1 more source

Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]

open access: yes, 2010
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel   +16 more
core   +1 more source

Analysis of extracellular RNA by digital PCR

open access: yesFrontiers in Oncology, 2014
The transfer of extracellular RNA is emerging as an important mechanism for intracellular communication. The ability for the transfer of functionally active RNA molecules from one cell to another within vesicles such as exosomes enables a cell to ...
Kenji eTakahashi   +4 more
doaj   +1 more source

Transfer RNA-derived small RNAs in tumor microenvironment

open access: yesMolecular Cancer, 2023
Transfer RNAs (tRNAs) are a class of non-coding RNAs responsible for amino acid translocation during protein synthesis and are ubiquitously found in organisms.
Mei Yang   +5 more
doaj   +1 more source

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

open access: yes, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W.   +3 more
core   +1 more source

Complete chloroplast genome of Chondria tumulosa (Ceramiales, Rhodophyta), a recently described cryptogenic species with invasive traits from Papahānaumokuākea Marine National Monument, Hawaiʻi

open access: yesMitochondrial DNA. Part B. Resources, 2021
The complete chloroplast genome of Chondria tumulosa, a red alga from Manawai (Pearl and Hermes Atoll), Hawai‘i, was determined and analyzed using next-generation sequencing and de novo assembly approaches. The chloroplast genome sequence of C.
Monica O. Paiano   +4 more
doaj   +1 more source

Nanodelivery of a functional membrane receptor to manipulate cellular phenotype. [PDF]

open access: yes, 2018
Modification of membrane receptor makeup is one of the most efficient ways to control input-output signals but is usually achieved by expressing DNA or RNA-encoded proteins or by using other genome-editing methods, which can be technically challenging ...
Baikoghli, Mo   +7 more
core   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Monitoring Real-time Temperature Dynamics of a Short RNA Hairpin Using Förster Resonance Energy Transfer and Circular Dichroism

open access: yesBio-Protocol, 2021
RNA secondary structures are highly dynamic and subject to prompt changes in response to the environment. Temperature in particular has a strong impact on RNA structural conformation, and temperature-sensitive RNA hairpin structures have been exploited ...
Martin Balcerowicz   +2 more
doaj   +1 more source

Transfer RNA genes experience exceptionally elevated mutation rates. [PDF]

open access: yes, 2018
Transfer RNAs (tRNAs) are a central component for the biological synthesis of proteins, and they are among the most highly conserved and frequently transcribed genes in all living things.
Corbett-Detig, Russell B   +5 more
core  

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