Results 251 to 260 of about 218,333 (309)

Molecular Maneuvers and Host Sabotage: A Comprehensive Review of CSFV's Multifaceted Strategies to Subvert Immune Defenses and Cellular Metabolism. [PDF]

Viruses
Sun W, Xu L, Li J.
europepmc   +1 more source

Reduced YTHDF2 inhibits PD-L1 expression by stabilizing m⁶A-containing SPOP mRNA in colorectal cancer. [PDF]

Cell Death Dis
Xu X, Chen H, Zhao R, Xie J, Liu H, Xie B, Lou J, Wang H, Wu X, Han W, Pan H, Shen J.   +11 more
europepmc   +1 more source

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, Volume 101, Issue 4, Page 784-793, April 2026.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

Small Molecule‐Based Conditional Gene Regulation: Advances and Applications

Chemistry–Methods, Volume 6, Issue 4, April 2026.
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari, Riddhima Sharma, Priyanka Swami, Ambadas B. Rode   +3 more
wiley   +1 more source

Ribo-Seq Analysis-Based Elucidation of the Dynamic Translation Landscape of Yak Ovarian Tissues in Different Reproductive Stages. [PDF]

FASEB J
Hu L, Guo S, Cao M, Xiong L, Ding Z, Kang Y, Zhang B, Cai B, Pei J, Guo X.   +9 more
europepmc   +1 more source

Epigenetic Alterations Beyond CpG Islands in Periodontitis: In Silico Study of DNA Methylation Data

Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives To classify differentially methylated CpG sites in periodontitis based on methylation shift direction and location relative to CpG islands. Material and Methods We integrated DNA methylation data from 65 gingival samples (31 periodontitis, 34 healthy) from three GEO datasets.
Koki Yoshida, Gowri Sivaramakrishnan, Farah Asa'ad   +2 more
wiley   +1 more source

Synthetic Pentatricopeptide Repeat Proteins: Building a Toolkit for Precise RNA Control. [PDF]

Int J Mol Sci
Lombana JM, Hanson MR, Bentolila S.
europepmc   +1 more source

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

3'UTR Mapping Reveals Alternative Polyadenylation in Right Ventricular Failure. [PDF]

Circ Res
Neupane R, Natarajan K, Suarez EE, Pownall HJ, Huang KL, Wagner EJ, Verma AK, Majji R, Yalamanchili HK, Guha A, Thandavarayan RA.   +10 more
europepmc   +1 more source

The 5‐Methylcytosine RNA Modification in Hepatitis B Virus‐Negative Hepatocellular Carcinoma: Insights From Long‐Read Nanopore Sequencing

Molecular Carcinogenesis, Volume 65, Issue 4, Page 397-406, April 2026.
ABSTRACT 5‐Methylcytosine (m5C) RNA modification contributes to tumor initiation and progression. However, its transcriptome‐wide distribution patterns and biological implications in hepatitis B virus (HBV)‐negative hepatocellular carcinoma (HCC) remain poorly understood.
Tianhan Sun, Liying Zhou, XiaoQing Li, Ryan Xiao, Gaoyuan Sun, Lili Zhang, Yifei Li, Wei Huang, Yayu Li, Lu Kuai, Xuanmei Luo, Hongyuan Cui, Meng Chen   +12 more
wiley   +1 more source