Results 281 to 290 of about 218,333 (309)
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Untranslated Nucleotide Sequence at the 5′-End of R 17 Bacteriophage RNA
Nature, 1970The 5′-terminal sequence of 74 nucleotides reported here does not seem to be involved in the synthesis of phage specific proteins but is probably concerned in the replication of R17 RNA. It is also of comparative interest—the sequence is strikingly similar to the corresponding section of Qβ phage RNA.
J M, Adams, S, Cory
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The 3′ untranslated region of messenger RNA: A molecular ‘hotspot’ for pathology?
Nature Medicine, 2000The role of the 3' untranslated region in posttranscriptional regulation of mRNA expression is being elucidated. Here we describe diseases arising from anomalies in this region, that affect the expression of one or more genes.
Conne, Béatrice +2 more
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Genetic complementation of radiation response by 3 untranslated regions (UTR) of RNA
International Journal of Radiation Biology, 1996The molecular basis of radiosensitivity was studied using a cDNA complementation approach to correct radiosensitivity in cells. Four cDNAs of sizes 1.6, 2.0, 2.2 and 2.5 kb were isolated that corrected several aspects of the phenotype of cells from patients with the human genetic disorder ataxia-telangiectasia, characterized by hypersensitivity to ...
Chen, P. +10 more
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Molecular Cloning and Sequence Analysis of a Human Untranslated Alu-Containing RNA
DNA Sequence, 2001A cDNA, designated LNX1, has been identified by subtractive hybridization on the basis that it is expressed in normal human prostate but not in LNCaP cells. Sequence analysis revealed that it contained two Alu repetitive sequences but no long open reading frame. Hence, it belongs to a class of untranslated Alu-containing RNAs. LNX1 is expressed in most
S C, Kwok, I, Daskal
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Untranslated Leader Sequences and Enhanced Messenger RNA Translational Efficiency
1990The analysis of gene regulation has been facilitated by model experimental systems which represent the extremes of a particular mechanism; that is, by identifying examples of controls which function either with extraordinary efficiency or not at all, investigators are provided with a system which might be manipulated to characterize the underlying ...
Lee Gehrke, Stephen A. Jobling
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An initiation signal in the 5′ untranslated leader sequence of encephalomyocarditis virus RNA
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1990A 593 nucleotide fragment of the 5' leader of encephalomyocarditis virus RNA (EMCV-RNA) was linked to the SP6 promoter and inserted upstream of the reporter gene chloramphenicol acetyltransferase (CAT). The presence of the 5'-UTR of EMCV-RNA in the RNA transcripts, made in vitro with the SP6 polymerase, resulted in a strong translational enhancement ...
Oudshoorn, P +3 more
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Deletion analysis of the 5' untranslated leader sequence of tobacco mosaic virus RNA
Journal of Virology, 1991To determine the sequences essential for viral multiplication in the 5' untranslated leader sequence of tobacco mosaic virus RNA, mutant TMV-L (a tomato strain) RNAs which carry several deletions in this 71-nucleotide sequence were constructed by an in vitro transcription system and their multiplication was analyzed by introducing mutant RNA into ...
N, Takamatsu +5 more
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Translation of HIV-1 unspliced RNA is regulated by 5′ untranslated region structure
Journal of VirologyABSTRACT HIV-1 must generate infectious virions to spread to new hosts and HIV-1 unspliced RNA (HIV-1 RNA) plays two central roles in this process. HIV-1 RNA serves as an mRNA that is translated to generate proteins essential for particle production and replication, and it is packaged into particles as
Zetao Cheng +9 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Transcriptomics: Translated and Untranslated RNA
2008David W. Ussery +2 more
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