Results 141 to 150 of about 870,257 (232)

Zooming in and out: Exploring RNA Viral Infections with Multiscale Microscopic Methods. [PDF]

Viruses
Lyu CA, Shen Y, Zhang P.
europepmc   +1 more source

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

Advanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı, Songjin Oh, Eunae Kim, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man Jeong Paik, Hangun Kim   +7 more
wiley   +1 more source

Scalable control of stem cell fate by riboswitch-regulated RNA viral vector without genomic integration. [PDF]

Mol Ther
Kim N, Yokobayashi Y.
europepmc   +1 more source

VipariNama: RNA viral vectors to rapidly elucidate the relationship between gene expression and phenotype. [PDF]

Plant Physiol, 2021
Khakhar A, Wang C, Swanson R, Stokke S, Rizvi F, Sarup S, Hobbs J, Voytas DF.   +7 more
europepmc   +1 more source

Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model

Advanced Therapeutics, EarlyView.
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika, Hyun Park, Eunjin Huh, Changyoon Baek, Shin‐Gyu Cho, Kwang‐Hwan Jung, Junhong Min, Kwanwoo Shin   +7 more
wiley   +1 more source

Biological and Social Predictors of HIV-1 RNA Viral Suppression in ART Treated PWLH in Sub-Saharan Africa. [PDF]

Trop Med Infect Dis
Gandla S, Nakka R, Khan RA, Bose E, Ghebremichael M.   +4 more
europepmc   +1 more source

Severe Acute Respiratory Syndrome Coronavirus 2 Total and Subgenomic RNA Viral Load in Hospitalized Patients. [PDF]

J Infect Dis, 2021
Dimcheff DE, Valesano AL, Rumfelt KE, Fitzsimmons WJ, Blair C, Mirabelli C, Petrie JG, Martin ET, Bhambhani C, Tewari M, Lauring AS.   +10 more
europepmc   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source

SegVir: Reconstruction of Complete Segmented RNA Viral Genomes from Metatranscriptomes. [PDF]

Mol Biol Evol
Tang X, Shang J, Chen G, Chan KHK, Shi M, Sun Y.   +5 more
europepmc   +1 more source

The ratio between SARS-CoV-2 RNA viral load and culturable viral titer differs depending on stage of infection

, 2023
Porter MK, Viloria Winnett A, Hao L, Shelby N, Reyes JA, Schlenker NW, Romano AE, Tognazzini C, Feaster M, Goh Y, Gale M, Ismagilov RF.   +11 more
europepmc   +1 more source