Results 21 to 30 of about 8,817,235 (253)
Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]
, 2012 tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena +3 more
core +1 more source
BioTechniques, 2009 Use of RNA affinity chromatography is commonly used to identify RNA binding proteins that interact with specific RNA cis-elements that function in post-transcriptional gene regulation.
Ruben H. Hovhannisyan, Russ P. Carstens
doaj +1 more source
A splicing-dependent transcriptional checkpoint associated with prespliceosome formation [PDF]
, 2014 There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown.
Chathoth, Keerthi T +3 more
core +1 more source
Microbiology Spectrum, 2022 Proteomic profiling of RNA-binding proteins in Leishmania is currently limited to polyadenylated mRNA-binding proteins, leaving proteins that interact with nonadenylated RNAs, including noncoding RNAs and pre-mRNAs, unidentified.
Karunakaran Kalesh +5 more
doaj +1 more source
Regulatory Effects of RNA-Protein Interactions Revealed by Reporter Assays of Bacteria Grown on Solid Media. [PDF]
Biosensors (Basel)This article belongs to the Special Issue Microbial Biosensor: From Design to Applications.Reporter systems are widely used to study biomolecular interactions and processes in vivo, representing one of the basic tools used to characterize synthetic ...
Pérez-Ropero G +6 more
europepmc +2 more sources
L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy [PDF]
, 2006 Ribosomal proteins are assumed to stabilize specific RNA structures and promote compact folding of the large rRNA. The conformational dynamics of the protein between the bound and unbound state play an important role in the binding process.
Wöhnert, Jens +9 more
core +2 more sources
, 2022 S.20-38Noncoding RNAs form an indispensible component of the cellular information processing networks, a role that crucially depends on the specificity of their interactions among each other as well as with DNA and protein. Patterns of intramolecular and
Stadler, Peter F., Marz, Manja
core +1 more source
Structure of a rare non-standard sequence k-turn bound by L7Ae protein [PDF]
, 2014 Kt-23 from Thelohania solenopsae is a rare RNA kink turn (k-turn) where an adenine replaces the normal guanine at the 2n position. L7Ae is a member of a strongly conserved family of proteins that bind a range of k-turn structures in the ribosome, box C/D
Huang, Lin, Lilley, David M J; id_orcid
core +1 more source
Identification of proteins binding coding and non-coding human RNAs using protein microarrays
BMC Genomics, 2012 Background The regulation and function of mammalian RNAs has been increasingly appreciated to operate via RNA-protein interactions. With the recent discovery of thousands of novel human RNA molecules by high-throughput RNA sequencing, efficient methods ...
Siprashvili Zurab +6 more
doaj +1 more source
Analysis of High-Throughput Data - Protein-Protein Interactions, Protein Complexes and RNA Half-life [PDF]
, 2009 The development of high-throughput techniques has lead to a paradigm change in biology from the small-scale analysis of individual genes and proteins to a genome-scale analysis of biological systems.
Friedel, Caroline Christina
core +1 more source