Results 281 to 290 of about 2,365,116 (344)
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Artificial intelligence-assisted RNA-binding protein signature for prognostic stratification and therapeutic guidance in breast cancer. [PDF]
Zhao Y+8 more
europepmc +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
CMSS1: A RNA binding protein with pivotal roles in non-small cell lung cancer progression and prognosis. [PDF]
Fan Z, Liu W, Gao Z, Liu Y, Hai H, Lv Z.
europepmc +1 more source
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan+4 more
wiley +1 more source
ELAV/Hu RNA-binding protein family: key regulators in neurological disorders, cancer, and other diseases. [PDF]
Wutikeli H, Xie T, Xiong W, Shen Y.
europepmc +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Protein nanoparticles as potent delivery vehicles for polycytosine RNA-binding protein one. [PDF]
Zhao ZY, Luo PL, Guo X, Huang ZW.
europepmc +1 more source
Yeast mitochondrial NAD+-dependent isocitrate dehydrogenase is an RNA-binding protein
S.D.J. Elzinga+4 more
openalex +2 more sources