Results 261 to 270 of about 1,861,609 (310)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Alpha-synuclein abundance and localization are regulated by the RNA-binding protein PUMILIO1. [PDF]

Cell Rep
Cabaj M, Mazzara PG, Gaertner ZA, Wang R, Pauers MM, Randolph LK, Roque CG, Feeney S, Raimo S, de Prisco N, Chemiakine A, Wang X, Singh RK, Rajasekaran S, Yalamanchili HK, Miles W, Baldwin K, Zhang C, Harms MB, Khurana V, Brandt V, Hengst U, Awatramani R, Gennarino VA.   +23 more
europepmc   +1 more source

Cold inducible RNA binding protein promotes fibroblast activation and its inhibition represents a potential therapeutic target in pulmonary fibrosis. [PDF]

Sci Rep
Mochizuka Y, Hozumi H, Watanabe H, Fukada A, Naoi H, Inoue Y, Yasui H, Suzuki Y, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Suda T.   +13 more
europepmc   +1 more source

YTH N6-methyladenosine RNA binding protein 2 mediated m⁶A modification of circHIPK2 promotes cellular senescence and osteoarthritis progression by inhibiting autophagy. [PDF]

Mol Biomed
Long D, Lin Z, Li Z, Li M, Zhao X, Deng Z, Jiang Z, Li W, Zhong Y, He A, Xu Y, Mao G, Kang Y.   +12 more
europepmc   +1 more source

Cold-inducible RNA binding protein ameliorates oxygen-glucose deprivation-induced hippocampal neuron injury through anti-apoptotic and anti-oxidative pathways. [PDF]

PeerJ
Chen L, Yao F, Cheng H, Guo M, Gao Y, Cai S, Duan M.   +6 more
europepmc   +1 more source

Correction: <i>RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer</i>. [PDF]

Gut
europepmc   +1 more source

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RNA-binding protein kinetics

Nature Methods, 2021
KIN-CLIP allows determination of binding and dissociation kinetics of RNA-binding proteins in cells.
openaire   +2 more sources

Plant RNA-binding proteins

Molecular Biology Reports, 1990
We have recently shown that although pre-mRNA splicing in plants shares some features in common with splicing in vertebrates, there are some crucial differences. In plants there is a requirement for a general enrichment for A+U within the intron and there is no requirement for a 3 ' polypyrimidine tract (Goodall and Filipowicz, 1989).
G, Goodall, J, Levy, M, Mieszczak, W, Filipowicz   +3 more
openaire   +2 more sources

Nuclear RNA-binding Proteins

1991
Publisher Summary The control of gene expression involves several steps at which specific sequences in pre-mRNA transcripts, as well as those in small RNA molecules, are recognized by proteins. RNA-binding proteins can be expected to mediate interactions in a variety of cellular processes, including those occurring in the transcription complex, the ...
J D, Keene, C C, Query
openaire   +2 more sources