Results 281 to 290 of about 1,875,767 (314)

RNA-binding proteins in cellular senescence

Mechanisms of Ageing and Development, 2023
Cellular senescence is a state of irreversible cell cycle arrest that is triggered and controlled by various external and/or internal factors. Among them, the regulation of senescence-associated genes is an important molecular event that plays a role in senescence.
Dahyeon Koh, Hyeong Bin Jeon, Chaehwan Oh, Ji Heon Noh, Kyoung Mi Kim   +4 more
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RNA-binding proteins mind the GAPs

Nature Immunology, 2017
Increased expression of the ubiquitin ligase TRAF6 in hematopoietic stem cells promotes activity of the GTP-binding protein Cdc42 and consequent diminished function of hematopoietic stem cells by ubiquitination of the RNA-binding protein hnRNP-A1, which leads to an inability to properly process pre-mRNA encoding Cdc42-inhibitory GTPase-activating ...
Martin Turner, Elisa Monzón-Casanova
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Motif models for RNA-binding proteins

Current Opinion in Structural Biology, 2018
Identifying the binding preferences of RNA-binding proteins (RBPs) is important in understanding their contribution to post-transcriptional regulation. Here, we review the current state-of-the art of RNA motif identification tools for RBPs. New in vivo and in vitro data sets provide sufficient statistical power to enable detection of relatively long ...
Alexander, Sasse, Kaitlin U, Laverty, Timothy R, Hughes, Quaid D, Morris   +3 more
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The RNA-binding proteins

2015
This chapter details how RNA-binding proteins package RNA, protect RNA, organize RNA, and prepare RNA for post-transcriptional processes. It describes different kinds of RNA-binding and auxiliary domains that enable RNA-binding proteins to bind RNA in a versatile way.
David Elliott, Michael Ladomery
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RNA-binding proteins of bovine rotavirus

Journal of Virology, 1986
Two major bovine rotavirus proteins have RNA-binding activity as shown by an RNA overlay-protein blot assay. Of the six proteins in purified virions, only one showed RNA-binding activity. This 92,000-molecular-weight (92K) protein was present in both single- and double-shelled particles.
J F, Boyle, K V, Holmes
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RNA-binding proteins of mammalian mitochondria

Mitochondrion, 2003
A UV-cross-linking assay was used to identify RNA-binding proteins in mammalian mitochondria. A number of these proteins were detected ranging in molecular mass from 15 to 120 kDa. All of the mRNA-binding activities were localized to the matrix except for two proteins which are primarily associated with the inner membrane.
Emine Cavdar, Koc, Linda L, Spremulli
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RBM4: A multifunctional RNA-binding protein

The International Journal of Biochemistry & Cell Biology, 2009
RBM4, also known as Lark, was described initially as having a role in circadian rhythm control in Drosophila. In the last 5 years data have emerged from studies of mammalian cells. It is now clear that RBM4 is an RNA-binding protein involved in diverse cellular processes that include alternative splicing of pre-mRNA, translation, and RNA silencing. Its
M Andrea, Markus, Brian J, Morris
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Understanding RNA-binding proteins

Seminars in Cancer Biology, 2022
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RNA-Binding Proteins in Heart Development

2014
RNA-binding proteins (RBPs) are key players of posttranscriptional regulation occurring during normal tissue development. All tissues examined thus far have revealed the importance of RBPs in the regulation of complex networks involved in organ morphogenesis, maturation, and function. They are responsible for controlling tissue-specific gene expression
Jimena, Giudice, Thomas A, Cooper
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Structures of RNA-binding proteins

Quarterly Reviews of Biophysics, 1997
J G, Arnez, J, Cavarelli
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