Results 271 to 280 of about 987,281 (377)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2010
P. Gong, O. Peersen
semanticscholar   +1 more source

Biomolecular Condensates as Emerging Biomaterials: Functional Mechanisms and Advances in Computational and Experimental Approaches

open access: yesAdvanced Materials, EarlyView.
Integration of computational and experimental approaches for deciphering the underlying mechanism of biomolecular condensates and potential biomaterials design (Created in Biorender. Raza, Z. (2025) https://BioRender.com/irgmeqi). Abstract Biomolecular condensates, a ubiquitous class of biomaterials found in living cells, have been shown to be ...
Qiang Zhu   +10 more
wiley   +1 more source

Exploring Echinacea angustifolia for anti-viral compounds against Zika virus RNA-dependent RNA polymerase: a computational study. [PDF]

open access: yesSci Rep
El-Daly MM   +7 more
europepmc   +1 more source

Nanoinjection Platform for Drug Delivery in Breast Cancer Therapeutics

open access: yesAdvanced Materials Interfaces, EarlyView.
A schematic shows Nanoarchaeosomes loaded with doxorubicin (NAD) delivered via silicon nanotubes (SiNTs) into MCF‐7 cells, triggering apoptosis and necrosis. Released doxorubicin generates ROS, disrupts mitochondria, and intercalates DNA. This dual‐action nanoinjection enhances cytotoxicity and improves breast cancer therapy efficacy.
Kaviya Vijayalakshmi Babunagappan   +8 more
wiley   +1 more source

Sofosbuvir: A Potential Treatment for Ebola

open access: yesFrontiers in Pharmacology, 2018
Sandra E. Reznik   +3 more
doaj   +1 more source

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