Results 131 to 140 of about 3,624,287 (199)

Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]

, 2013
RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, M., Basel Khraiwesh, Khraiwesh, Basel, Muhammad Arif, Khraiwesh, B., Arif, Muhammad Asif, Frank, W., Frank, Wolfgang, Wolfgang Frank   +8 more
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Thiolutin Derivatives as inhibitor of RNA-Dependent RNA Polymerase (RdRP) of Hepatitis C Virus: An In-silico Approach [PDF]

Annals of Antivirals and Antiretrovirals, 2018
Docking study of few Thiolutin derivatives, which originally act as Hepatitis C Virus RNA Dependent RNA Polymerase (RdRP) inhibitor, was performed by using AutoDock Vina. The docking studies reveal that thiolutin interacted with Hepatitis C Virus RNA Dependent RNA Polymerase through hydrogen bonding as well as hydrophobic interactions.
openaire   +1 more source

Roles of Cellular RNA-Dependent RNA Polymerases in Endogenous Small RNA Pathways in Caenorhabditis elegans: A Dissertation [PDF]

, 2010
The RNA interference (RNAi) pathway in Caenorhabditis elegans is a two-step, small RNA-mediated silencing pathway. Unlike in other organisms, Dicer processing of double-stranded RNA into small interfering (si) RNAs is not sufficient in worms to induce ...
Vasale, Jessica J.
core   +1 more source

The Paramyxovirus Polymerase Complex as a Target for Next-Generation Anti-Paramyxovirus Therapeutics

Frontiers in Microbiology, 2015
The paramyxovirus family includes major human and animal pathogens, including measles virus, mumps virus, and human respiratory syncytial virus (RSV), as well as the emerging zoonotic Hendra and Nipah viruses.
Richard K Plemper, Robert eCox
doaj   +1 more source

Distinct roles of non-canonical poly(A) polymerases in RNA metabolism [PDF]

, 2009
Trf4p and Trf5p are non-canonical poly(A) polymerases and are part of the heteromeric protein complexes TRAMP4 and TRAMP5 that promote the degradation of aberrant and short-lived RNA substrates by interacting with the nuclear exosome. To assess the level
Schenk, L., Keller Walter, Vanacova, S., Blank Diana, Scherrer, T., San Paolo, Salvatore, Keller, W., André P Gerber, San Paolo, S., Gerber André P., Salvatore San Paolo, Tanja Scherrer, Diana Blank, Blank, Diana, Gerber, A. P., Blank, D., Scherrer Tanja, Gerber, André P., Schenk Luca, Walter Keller, Luca Schenk, Scherrer, Tanja, Vanacova Stepanka, Stepanka Vanacova, Vanacova, Stepanka, Paolo Salvatore San, Keller, Walter, Schenk, Luca   +27 more
core   +1 more source

RNA Dependent RNA Polymerase (RdRP) [PDF]

Science-Business eXchange, 2008
openaire   +2 more sources

ORF8 protein in SARS-CoV-2 might be a non-canonical RNA dependent RNA polymerase (RdRp)

, 2020
No current treatment options were successful in containing the ongoing pandemic COVID-19 caused by SARS-CoV-2. It is essential to understand the molecular players of SARS-CoV-2 to find a suitable treatment method and to develop an effective antiviral drug as early as possible.
Venkatesan Ramya, Karuppiah Prakash Shyam, Rajkumar Prabhakaran, Vignesh Kalimuthu, Sathya Priya Krishnamoorthy, Balamuthu Kadalmani   +5 more
openaire   +1 more source

Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs [PDF]

, 2010
Theis C, Janssen S, Giegerich R. Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs. In: Moulton V, Singh M, eds. Algorithms in Bioinformatics. 10th international workshop (WABI 2010), proceedings. Lecture Notes in Bioinformatics. Vol
Corinna Theis, Theis, Corinna, Moulton, Vincent, Singh, Mona, Stefan Janssen, Janssen, Stefan ; https://orcid.org/, Robert Giegerich, Giegerich, Robert   +7 more
core   +1 more source

A Conserved GA Element in TATA-Less RNA Polymerase II Promoters [PDF]

, 2011
Initiation of RNA polymerase (Pol) II transcription requires assembly of the pre-initiation complex (PIC) at the promoter. In the classical view, PIC assembly starts with binding of the TATA box-binding protein (TBP) to the TATA box.
Hartmann, H., Kurth, F., Cramer, P., Hartmann, Holger, Hartmann Holger, Martin Dietmar E., Söding Johannes, Seizl, Martin, Kurth Fabian, Martin, D., Martin Seizl, Fabian Kurth, Cramer Patrick, Hoeg Friederike, Söding* Patrick Cramer, Martin, Dietmar E., Hoeg, F., Cramer, Patrick, Patrick Cramer, Soeding, J., Johannes Söding, Holger Hartmann, Hoeg, Frederike, Kurth, Fabian, Söding, J., Seizl, M., Seizl Martin, Söding, Johannes, Dietmar E Martin, Friederike Hoeg, Martin, D. E., Hoeg, Friederike, Dietmar E. Martin   +32 more
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The function of the protein phosphatase Glc7p in transcription termination, RNA processing and transcriptional regulation of ribosomal protein genes [PDF]

, 2007
Gene transcription in general can be subdivided into three main phases: transcription initiation, elongation and termination. The enzyme that accomplishes transcription of protein coding genes, snRNAs and snoRNAs is RNA polymerase II (RNAP II).
Röck, Salome
core   +1 more source