Results 141 to 150 of about 34,592 (189)

Meeting review : ESF workshop on "Impact of nucleic acid chemistry on gene function analysis: antisense, aptamers, ribozymes and RNAi" [PDF]

, 2008
The shortage of functional information compared to the abundance of sequence information characterizes today’s situation in functional genomics. For many years the knock-down of a gene’s product has been the most powerful way of analysing its function ...
Engels, Joachim W. (Prof. Dr.), Heermeier, Kathrin, Prydz, Hans, Reinhard-Rupp, Jutta   +3 more
core  

Structural basis of Nipah virus RNA synthesis

Nature Communications
Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its RNA-dependent RNA polymerase (RdRp) complex, consisting of the
Fernanda A. Sala, Katja Ditter, Olexandr Dybkov, Henning Urlaub, Hauke S. Hillen   +4 more
doaj   +1 more source

Comparative molecular docking and simulation analysis of molnupiravir and remdesivir with SARS-CoV-2 RNA dependent RNA polymerase (RdRp). [PDF]

Bioinformation, 2021
Patil SM, Maruthi KR, Bajpe SN, Vyshali VM, Sushmitha S, Akhila C, Ramu R.   +6 more
europepmc   +1 more source

Dengue virus RNA-dependent RNA polymerase (RdRp) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Influenza RNA-Dependent RNA Polymerase (RdRp) Inhibitors: Potential New Therapy for Influenza Treatment [PDF]

ACS Medicinal Chemistry Letters, 2013
openaire   +2 more sources

An adenosine analog shows high antiviral potency against coronavirus and arenavirus mainly through an unusual base pairing mode

Nature Communications
By targeting the essential viral RNA-dependent RNA polymerase (RdRP), nucleoside analogs (NAs) have exhibited great potential in antiviral therapy for RNA virus-related diseases.
Xiaoying Jia, Xuping Jing, Ming Li, Minli Gao, Yao Zhong, Entao Li, Yang Liu, Rui Li, Guoqiang Yao, Qiaojie Liu, Minmin Zhou, Yuxia Hou, Linfeng An, Yibao Hong, Shanshan Li, Jiancun Zhang, Wei Wang, Kaiming Zhang, Peng Gong, Sandra Chiu   +19 more
doaj   +1 more source

In silico structural elucidation of the rabies RNA-dependent RNA polymerase (RdRp) toward the identification of potential rabies virus inhibitors. [PDF]

J Mol Model, 2021
Kiriwan D, Choowongkomon K.
europepmc   +1 more source

Targeting the SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp) With Synthetic/Designer Unnatural Nucleoside Analogues: An In Silico Study

, 2023
Bag SS, Sinha S, Dutta S, Baishya HJ, Paul S.   +4 more
europepmc   +1 more source

Comparing Force Field Treatments in QM/MM Studies of the SARS-CoV-2 RNA-Dependent RNA Polymerase (RdRp) Mechanism. [PDF]

J Chem Theory Comput
Roca M, Maghsoud Y, Cisneros GA, Świderek K, Moliner V.   +4 more
europepmc   +1 more source

Deciphering inhibitory mechanism of coronavirus replication through host miRNAs-RNA-dependent RNA polymerase (RdRp) interactome

, 2022
Morenikeji OB, Adegbaju MS, Okoh OS, Babalola AE, Grytsay A, Braimah OA, Akinyemi MO, Thomas BN.   +7 more
europepmc   +1 more source