Results 161 to 170 of about 57,300 (174)

Potential use of RNA-dependent RNA polymerase (RdRp) inhibitor against COVID-19 infection

2020
Favipiravir, an inhibitor of RNA-dependent RNA polymerase used against the Japanese flu, was recently suggested as a potential COVID-19 inhibitor. Since Favipiravir targets a critical and a viral specific process, using it as a treatment could be beneficial in slowing the outbreak.
Santerre, Maryline, Allen, Charles, Arjona, Sterling, bassel e sawaya,   +3 more
openaire   +1 more source

Conserved amino acids in HCoV-HKU1 and SARS-Cov2 at RNA-dependent RNA polymerase (RdRp) motifs

2021
A novel and related to severe acute respiratory syndrome associated coronavirus (SARS-CoV2) has been identified as an infectious coronavirus originating from a Wuhan seafood market and rapidly spreading into and beyond China. While non-conserved regions of viral genome can lead to novel coronavirus subtypes, conserved regions are also very important ...
ATASEVER ARSLAN, Belkis, GÜNAL SADIK, Gamze, TİMUÇİN, Ahmet Can, KUŞOĞLU GÜLTEKİN, Seda, YANIK, Ayşegül   +4 more
openaire   +1 more source

Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA‐dependent RNA polymerase (RdRp) inhibition: an in-silico analysis

Journal of Biomolecular Structure and Dynamics, 2021
Satyam Singh, Md Fulbabu Sk, Avinash Sonawane   +2 more
exaly  

Cordycepin as a Promising Inhibitor of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp)

Current Medicinal Chemistry, 2022
openaire   +2 more sources

Evolution of the RNA-dependent RNA polymerase (RdRP) genes: duplications and possible losses before and after the divergence of major eukaryotic groups.

Gene, 2009
Jie Zong, Xuan Yao, Jinyuan Yin, Dabing Zhang, Hong Ma   +4 more
semanticscholar   +1 more source

Finding potential inhibitors against RNA-dependent RNA polymerase (RdRp) of bovine ephemeral fever virus (BEFV): an in-silico study

Journal of Biomolecular Structure and Dynamics, 2022
Shruti Pyasi, Nisha Amarnath Jonniya, Md Fulbabu Sk   +2 more
exaly  

Molecular Evolutionary Analyses of the RNA-Dependent RNA Polymerase (RdRp) Region and VP1 Gene in Human Norovirus Genotypes GII.P6-GII.6 and GII.P7-GII.6

Viruses, 2023
Ryusuke Kimura, Tatsuya Shirai, Toshiyuki Sugai   +2 more
exaly  

In silicoidentification of novel benzophenone–coumarin derivatives as SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitors

Journal of Biomolecular Structure and Dynamics, 2022
Shashank M Patil, Reshma Mary Martiz, Ramith Ramu   +2 more
exaly  

RdRp (RNA-dependent RNA polymerase): A key target providing anti-virals for the management of various viral diseases

Journal of Molecular Structure, 2022
Shelly Pathania, Ravindra K Rawal, Pankaj Kumar Singh   +2 more
exaly  

Interaction of Sesbania mosaic virus (SeMV) RNA‐dependent RNA polymerase (RdRp) with the p10 domain of polyprotein 2a and its implications in SeMV replication

FEBS Open Bio, 2014
Arindam Bakshi, H S Savithri
exaly