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In bacterial cells we find a variety of interacting macromolecules, among them RNAs and proteins. Not only small regulatory RNAs (sRNAs), but also small proteins have been increasingly recognized as regulators of bacterial gene expression.
Inam Ul Haq +2 more
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Template-Based Modeling of Protein-RNA Interactions. [PDF]
Protein-RNA complexes formed by specific recognition between RNA and RNA-binding proteins play an important role in biological processes. More than a thousand of such proteins in human are curated and many novel RNA-binding proteins are to be discovered.
Jinfang Zheng +3 more
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Computational tools to study RNA-protein complexes
RNA is the key player in many cellular processes such as signal transduction, replication, transport, cell division, transcription, and translation. These diverse functions are accomplished through interactions of RNA with proteins.
Sneha Bheemireddy +5 more
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RNA Proximity Labeling: A New Detection Tool for RNA–Protein Interactions
Multiple cellular functions are controlled by the interaction of RNAs and proteins. Together with the RNAs they control, RNA interacting proteins form RNA protein complexes, which are considered to serve as the true regulatory units for post ...
Ronja Weissinger +4 more
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Essential Assembly Factor Rpf2 Forms Novel Interactions within the 5S RNP in
Ribosome biogenesis is a highly complex and conserved cellular process that is responsible for making ribosomes. During this process, there are several assembly steps that function as regulators to ensure proper ribosome formation.
Anyango D. Kamina +3 more
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Virüslerin Kodladığı Uzun ve Kısa Kodlamayan RNA’lar
Yeni geliştirilen RNA dizileme teknolojileri ile yaklaşık son on yıldır, memeli genomlarının önceden çöp, ‘junk’ DNA olarak görülen kısımlarının aslında aktif olarak RNA’ya dönüştükleri gözlemlenmektedir.
Mehmet Kara
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Human telomerase RNA-protein interactions [PDF]
Telomere length is maintained in most eukaryotic cells by telomerase. The core components of this ribonucleoprotein (RNP) enzyme include a protein catalytic subunit, composed of motifs conserved among reverse transcriptases (RT), and an RNA subunit that contains a short template sequence essential for the synthesis of telomeric repeats. We developed an
F, Bachand, I, Triki, C, Autexier
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Transient DNA / RNA‐protein interactions [PDF]
The great pace of biomolecular structure determination has provided a plethora of protein structures, but not as many structures of nucleic acids or of their complexes with proteins. The recognition of DNA and RNA molecules by proteins may produce large and relatively stable assemblies (such as the ribosome) or transient complexes (such as DNA clamps ...
Francisco J, Blanco, Guillermo, Montoya
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Use of RNA affinity chromatography is commonly used to identify RNA binding proteins that interact with specific RNA cis-elements that function in post-transcriptional gene regulation.
Ruben H. Hovhannisyan, Russ P. Carstens
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Proteomic profiling of RNA-binding proteins in Leishmania is currently limited to polyadenylated mRNA-binding proteins, leaving proteins that interact with nonadenylated RNAs, including noncoding RNAs and pre-mRNAs, unidentified.
Karunakaran Kalesh +5 more
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