Results 11 to 20 of about 8,817,199 (297)

CRISPR-Guided Proximity Labeling of RNA–Protein Interactions [PDF]

Genes (Basel), 2022
Proximity labeling employs modified biotin ligases or peroxidases that produce reactive radicals to covalently label proximate proteins with biotin in living cells. The resulting biotinylated proteins can then be isolated and identified. A combination of
Zuowei Wang, Ren, Bingbing, Mingxing Lu, Yixiu Wang, Bingbing Ren, Wang, Zuowei, Lu, Mingxing, Wang, Yixiu   +7 more
core   +2 more sources

Decoding RNA–protein interactions using high-throughput methods [PDF]

RNA Biology
RNA-binding proteins (RBPs) constitute a diverse class of proteins essential for every stage of the gene expression process. Many RBPs are also linked to human diseases and pathologies.
Marianne Régis, Paola Pulcina, Dmitry A. Kretov   +2 more
doaj   +2 more sources

The Plethora of RNA–Protein Interactions Model a Basis for RNA Therapies [PDF]

Genes (Basel)
The notion of RNA-based therapeutics has gained wide attractions in both academic and commercial institutions. RNA is a polymer of nucleic acids that has been proven to be impressively versatile, dating to its hypothesized RNA World origins, evidenced by
Stephen J. Dansereau, Ricky P. Dartawan, Hua Cui, Jia Sheng   +3 more
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation [PDF]

FEBS Open Bio
Cellular RNAs are not linear single‐stranded stretches of nucleic acids as depicted in textbook cartoons but fold into secondary and tertiary structures through intra‐ and intermolecular base‐pairing.
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
doaj   +2 more sources

Temporal-iCLIP captures co-transcriptional RNA-protein interactions [PDF]

Nature Communications, 2023
Dynamic RNA-protein interactions govern the co-transcriptional packaging of RNA polymerase II derived transcripts. Here the authors use temporal-iCLIP which combines transcriptional synchronisation with UV cross-linking of RNA-protein complexes to reveal
Ross A. Cordiner, Yuhui Dou, Rune Thomsen, Andrii Bugai, Sander Granneman, Torben Heick Jensen   +5 more
doaj   +2 more sources

Viral RNA Interactome: The Ultimate Researcher’s Guide to RNA–Protein Interactions [PDF]

Viruses
RNA molecules in the cell are bound by a multitude of RNA-binding proteins (RBPs) with a variety of regulatory consequences. Often, interactions with these RNA-binding proteins are facilitated by the complex secondary and tertiary structures of RNA ...
Wesley A. Hanson, Gabriel A. Romero Agosto, Silvi Rouskin   +2 more
doaj   +2 more sources

Regulatory effects of RNA–protein interactions revealed by reporter assays of bacteria grown on solid media [PDF]

Biosensors (Basel)
This article belongs to the Special Issue Microbial Biosensor: From Design to Applications.Reporter systems are widely used to study biomolecular interactions and processes in vivo, representing one of the basic tools used to characterize synthetic ...
Pérez-Ropero, Guillermo, Andersson, Karl, Andersson, Karl,, Dolcemascolo, Roswitha, Buijs, Jos, Guillermo Pérez-Ropero, Anna Pérez-Ràfols, Pérez-Ropero, Guillermo,, Danielson, Helena,, U. Helena Danielson, Jos Buijs, Danielson, Helena, Buijs, Jos,, Roswitha Dolcemascolo, Guillermo Rodrigo, Danielson, U. Helena, Rodrigo, Guillermo, Pérez-Ràfols, Anna, Karl Andersson   +18 more
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PaRPI predicts RNA-Protein interactions from cross-protocol and cross-batch RNA-binding protein datasets [PDF]

Communications Biology
RNA-binding proteins (RBPs) play a pivotal role in the regulation of gene expression, with their interactions with RNA reflecting the biological functions and regulatory mechanisms.
Liangchen Peng, Lijun Quan, Lingkun Meng, Zhihong Zhang, Shengju Zhang, Zhijun Zhang, Yi Zhang, Qiufeng Chen, Bei Zhang, Lexin Cao, Tingfang Wu, Qiang Lyu   +11 more
doaj   +2 more sources

'Oming in on RNA–protein interactions [PDF]

Genome Biology, 2014
Welcome to the RBPome RNA has consistently broken dogmas, owing to its multitude of unexpected functions. However, RNA does faithfully adhere to one rule: it always functions through interactions with proteins. The studies in this issue focus on the rapidly expanding repertoire of diverse RNA– protein interactions [1] and their functional roles and ...
Rinn, John L, Ule, Jernej
openaire   +2 more sources

Transient DNA / RNA‐protein interactions [PDF]

The FEBS Journal, 2011
The great pace of biomolecular structure determination has provided a plethora of protein structures, but not as many structures of nucleic acids or of their complexes with proteins. The recognition of DNA and RNA molecules by proteins may produce large and relatively stable assemblies (such as the ribosome) or transient complexes (such as DNA clamps ...
Blanco, Francisco J., Montoya, Guillermo
openaire   +3 more sources