Results 121 to 130 of about 867,422 (305)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Study of regulatory models of RNA in RNA-protein phase separation condensation

open access: yes四川大学学报. 自然科学版
This modeling study aims to model the regulatory role of RNA in RNA-protein (PROT) phase separation condensation (PSC). First, based on diffusion kinetics and Hill kinetics, a novel theoretical model for dynamic RNA-PROT PSC is proposed.
HAN Tuo-Di   +3 more
doaj  

Poxvirus K7 Protein Adopts a Bcl-2 Fold: Biochemical Mapping of Its Interactions with Human DEAD Box RNA Helicase DDX3

open access: bronze, 2008
Arnout P. Kalverda   +6 more
openalex   +2 more sources

Emergent RNA-RNA interactions can promote stability in a facultative phototrophic endosymbiosis. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Jenkins BH   +7 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

CLASH Analyst: A Web Server to Identify In Vivo RNA-RNA Interactions from CLASH Data. [PDF]

open access: yesNoncoding RNA, 2022
Wu WS   +5 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

RNA-Protein Interaction Detection (RaPID) [PDF]

open access: hybrid, 2018
Muthukumar Ramanathan   +2 more
openalex   +1 more source

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