Results 181 to 190 of about 1,151,716 (261)

Integrated Bioinformatics Analysis of Differentially Expressed RNA-Binding Proteins in Human Gliomas. [PDF]

Cell Mol Neurobiol
Haque S, Mathkor DM, Babegi AS, Ahmad F, Arumugam M.   +4 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Dysregulated landscape of RNA-binding proteins in unexplained recurrent spontaneous abortion revealed by bulk and single-cell transcriptome. [PDF]

Sci Rep
Zhu Y, Chen D, Xu B, Wu X, Liang A, Yan Q.   +5 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

KnockRBP: an integrated multi-omics database of functional perturbation profiles for RNA-binding proteins. [PDF]

Nucleic Acids Res
Yang M, Li J, Liu J, Lu X, Zhou X, Xu Y.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Correction to 'RBPWorld for exploring functions and disease associations of RNA-binding proteins across species'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Targeting RNA binding proteins with small-molecule inhibitors: Advances, challenges, and therapeutic opportunities. [PDF]

Acta Pharm Sin B
Shi Y, Feng D, Zhou J, Liu L, Li X, Yuan Z, Wu J, Yao H.   +7 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

An updated compendium of Caenorhabditis elegans RNA-binding proteins and their regulation. [PDF]

G3 (Bethesda)
Peng F, Murray JI.
europepmc   +1 more source