Results 71 to 80 of about 2,163,835 (311)
BioTechniques, 2007 Proteins with RNA chaperone activity help RNAs to obtain their native conformations, and many of them are active in the two basic reactions—RNA annealing and strand displacement.
Lukas Rajkowitsch, Renée Schroeder
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Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]
, 2012 tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena +3 more
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New Methods in RNA Structural Biology: TELSAM Protein Chaperone Crystallography Applications to Folded RNA [PDF]
Structural DynamicsThe multifaceted roles of RNA in cellular function are becoming increasingly apparent, and the importance of deepening our understanding of the function and structure of ribozymes and non-enzymatic RNAs will continue to grow.
Jacob C Averett +4 more
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An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae
Nature Communications, 2022 Small regulatory RNAs (sRNAs) often act in concert with the RNA-chaperone Hfq to regulate the expression of multiple target transcripts in bacteria.
Michaela Huber +8 more
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RNA misfolding and the action of chaperones [PDF]
Frontiers in Bioscience, 2008 RNA folds to a myriad of three-dimensional structures and performs an equally diverse set of functions. The ability of RNA to fold and function in vivo is all the more remarkable because, in vitro, RNA has been shown to have a strong propensity to adopt misfolded, non-functional conformations.
openaire +2 more sources
RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +3 more
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Nature Communications, 2020 The (G4C2)-RNA hexanucleotide repeat expansion upstream of the start codon of the C9orf72 gene plays a critical role in familial ALS. The authors show that Sig1R, a ligand-regulated molecular chaperone, counteracts the aberrant nucleocytoplasmic ...
Pin-Tse Lee +8 more
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Chaperna: linking the ancient RNA and protein worlds
RNA Biology, 2021 As a mental framework for the transition of self-replicating biological forms, the RNA world concept stipulates a dual function of RNAs as genetic substance and catalyst.
Ahyun Son, Scott Horowitz, Baik L. Seong
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An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]
, 2007 RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid +4 more
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
, 2013 : OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes.
Taylor, James E. +28 more
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