Results 81 to 90 of about 2,163,835 (311)

Selective recruitment of stress-responsive mRNAs to ribosomes for translation by acetylated protein S1 during nutrient stress in Escherichia coli

Communications Biology, 2022
RNA molecular chaperone S1 is acetylated and selectively recruits stress-responsive mRNAs to the ribosome during nitrogen starvation in E. coli, revealing a translation regulation mechanism for nutrient stress adaptation.
Bai-Qing Zhang, Zong-Qin Chen, Yu-Qi Dong, Di You, Ying Zhou, Bang-Ce Ye   +5 more
doaj   +1 more source

Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons [PDF]

, 2020
Axonal protein synthesis has been shown to play a role in developmental and regenerative growth, as well as in the maintenance of the axoplasm in steady state.
Sotelo-Silveira, José Roberto, Farías, Joaquina, Sotelo Sosa, José Roberto, Holt, C. E.   +3 more
core   +3 more sources

Chaperone/usher machinery [PDF]

, 2012
Many virulence organelles of Gram-negative bacterial pathogens are assembled via the periplasmic chaperone/usher (CU) pathway. The assembly process is a complex task, involving secretion of organelle subunits via the two membranes and periplasm, subunit ...
Yu, Xiaodi
core   +1 more source

Advances in chaperone-assisted RNA crystallography using synthetic antibodies

BBA Advances, 2023
RNA molecules play essential roles in many biological functions, from gene expression regulation, cellular growth, and metabolism to catalysis. They frequently fold into three-dimensional structures to perform their functions.
Hasan Al Banna, Naba Krishna Das, Manju Ojha, Deepak Koirala   +3 more
doaj   +1 more source

Protein and RNA chaperones

Molecular Aspects of Medicine
Cells preserve macromolecular homeostasis by utilizing molecular chaperones that prevent aggregation or promote correct folding of protein and RNA. Here we discuss non-traditional proteinaceous chaperones like RNA-binding chaperones that work by modulating RNA structure, preventing aberrant interactions, and regulating intracellular granule dynamics ...
Bikash R. Sahoo, James CA. Bardwell
openaire   +2 more sources

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Richard M. Elliott, Böttcher, Bettina, Li, P., Dong, H., Li, Ping, Dong, Changjiang, Dong, Haohao, Elliott, R., Boettcher, Bettina, Elliott, Richard M., Bottcher, B., Haohao Dong, Bettina Böttcher, Ping Li, Elliott, Richard M, Dong, C., Changjiang Dong   +16 more
core   +1 more source

Role of RNA chaperones in virus replication

Virus Research, 2009
RNA molecules are functionally diverse in part due to their extreme structural flexibility that allows rapid regulation by refolding. RNA folding could be a difficult process as often molecules adopt a spatial conformation that is very stable but not biologically functional, named a kinetic trap.
Zuniga, Sonia, Sola, Isabel, Cruz, Jazmina L. G., Enjuanes, Luis   +3 more
openaire   +6 more sources

Diversity of bacterial small RNAs drives competitive strategies for a mutual chaperone

Nature Communications, 2022
Bacterial sRNAs compete for limited copies of an RNA chaperone. Here, real-time single-molecule imaging shows that pairwise interactions of sRNAs with Hfq determine if the sRNAs are actively exchanged or stably coexist on the shared protein.
Jorjethe Roca, Andrew Santiago-Frangos, Sarah A. Woodson   +2 more
doaj   +1 more source

Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module

Viruses, 2022
As for all non-segmented negative RNA viruses, rabies virus has its genome packaged in a linear assembly of nucleoprotein (N), named nucleocapsid. The formation of new nucleocapsids during virus replication in cells requires the production of soluble N ...
Francine C. A. Gérard, Jean-Marie Bourhis, Caroline Mas, Anaïs Branchard, Duc Duy Vu, Sylvia Varhoshkova, Cédric Leyrat, Marc Jamin   +7 more
doaj   +1 more source

The unusual glycine-rich C terminus of the Acinetobacter baumannii RNA chaperone Hfq plays an important role in bacterial physiology

Journal of Biological Chemistry, 2018
Acinetobacter baumannii is a Gram-negative nosocomial pathogen that causes soft tissue infections in patients who spend a long time in intensive care units.
Atin Sharma, V. Dubey, Rajnikant Sharma, Kuldip Devnath, V. Gupta, Jawed Akhter, Timsy Bhando, Aparna Verma, K. Ambatipudi, M. Sarkar, R. Pathania   +10 more
semanticscholar   +1 more source