Results 21 to 30 of about 1,912,865 (328)

Rice black-streaked dwarf virus-encoded P6 protein impairs OsPelota-mediated antiviral RNA decay defense via promoting OsSCE1b ubiquitination and degradation in rice. [PDF]

J Integr Plant Biol
Xie Y, Zeng M, Wang D, Gao SB, Li L, Zheng L, Zhang Y, Fei S, Zhang C, Wang Y, Zhou X, Wu J.   +11 more
europepmc   +3 more sources

Attacked from All Sides: RNA Decay in Antiviral Defense

Viruses, 2017
The innate immune system has evolved a number of sensors that recognize viral RNA (vRNA) to restrict infection, yet the full spectrum of host-encoded RNA binding proteins that target these foreign RNAs is still unknown.
Jerome M. Molleston, Sara Cherry
doaj   +2 more sources

Nonsense-mediated RNA decay: an emerging modulator of malignancy

Nature Reviews Cancer, 2022
Kun Tan, Miles F Wilkinson
exaly   +2 more sources

Structure-Mediated RNA Decay by UPF1 and G3BP1. [PDF]

Mol Cell, 2020
Fischer JW, Busa VF, Shao Y, Leung AKL.
europepmc   +2 more sources

A CRISPR-Cas9 knockout screening identifies IRF2 as a key driver of OAS3/RNase L-mediated RNA decay during viral infection. [PDF]

Proc Natl Acad Sci U S A
Oh S, Santiago G, Manjunath L, Li J, Bouin A, Semler BL, Buisson R.   +6 more
europepmc   +3 more sources

A novel nonsense variant in ARID1B causing simultaneous RNA decay and exon skipping is associated with Coffin-Siris syndrome. [PDF]

Hum Genome Var, 2022
Sofronova V, Fukushima Y, Masuno M, Naka M, Nagata M, Ishihara Y, Miyashita Y, Asano Y, Moriwaki T, Iwata R, Terawaki S, Yamanouchi Y, Otomo T.   +12 more
europepmc   +3 more sources

A Rapid Inducible RNA Decay system reveals fast mRNA decay in P-bodies

bioRxiv, 2023
RNA decay plays a crucial role in regulating mRNA abundance and gene expression. Modulation of RNA degradation is imperative to investigate an RNA’s function. However, information regarding where and how RNA decay occurs remains scarce, partially because
Lauren A. Blake, Yang Liu, Takanari Inoue, Bin Wu   +3 more
semanticscholar   +1 more source

SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome

RNA Biology, 2023
Nsp1 is a SARS-CoV-2 host shutoff factor that both represses cellular translation and promotes host RNA decay. However, it is unclear how these two activities are connected and interact with normal translation processes.
Soraya I. Shehata, Roy Parker
doaj   +1 more source

N(6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay

EMBO Reports, 2021
N6‐methyladenosine (m6A) modification of mRNA mediates diverse cellular and viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with nasopharyngeal carcinoma (NPC), 10% of gastric carcinoma, and various B‐cell lymphomas, in ...
Tian-Liang Xia, Xingyang Li, Xueping Wang, Yun-Jia Zhu, Hua Zhang, Weisheng Cheng, Mei-Ling Chen, Y. Ye, Yan Li, Ao Zhang, Dan-Ling Dai, Qianying Zhu, Li Yuan, Jian Zheng, Huilin Huang, Sibo Chen, Zhi-wen Xiao, Hong-bo Wang, Gaurab Roy, Qian Zhong, D. Lin, Y. Zeng, Jinkai Wang, Bo Zhao, B. Gewurz, Jianjun Chen, Zhixiang Zuo, M. Zeng   +27 more
semanticscholar   +1 more source

LTO1 and YAE1 regulate MHC-I expression via nonsense-mediated RNA decay in tumor cells. [PDF]

J Immunother Cancer
Yang Z, Meng Z, Liu S, Chen Y, Gan X, Zhang ZM, Luo X, Yan J, Chen H, Huang D, Huang L, Zeng X, Ma W, Liu J, Wang L, Huang H, Yang X, Hu M, Chen L, Du H, Leng Q, Qiu L, Wang X.   +22 more
europepmc   +3 more sources