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DEGRADATION OF MESSENGER RNA IN MAMMALIAN CELLS

Acta Endocrinologica, 1972
ABSTRACT Analyses of the response of hydrocortisone-induced tyrosine transaminase in cultured H-35 cells to inhibitors of translation (cycloheximide, puromycin) suggest: (1) that bound ribosomes stabilize messenger RNA in vivo; (2) that messenger is degraded at a rate determined by the rate of translation.
F T, Kenney, K L, Lee, C D, Stiles
openaire   +2 more sources

Structural organization of the RNA-degrading exosome

Current Opinion in Structural Biology, 2008
The RNA exosome participates in the degradation and processing of a wide range of RNA molecules. Recent advances in understanding how the exosome is organized and functions largely stem from structural studies. Crystal structures of archaeal exosomes bound to RNA and of the corresponding nine-subunit human exosome core show that the archaeal and ...
Lorentzen, E.; id_orcid 0000-0001-6493-7220   +2 more
openaire   +4 more sources

RNA and protein degradation in the aging process

Cellular Signalling
Aging involves a profound reorganization of metabolic processes, marked by a progressive decline in anabolic activity and a compensatory increase in catabolic flux. This imbalance drives cellular dysfunction and contributes to age-related phenotypes, including sarcopenia, anorexia, and sleep disturbances.
Junqiang, Lin   +7 more
openaire   +2 more sources

Degrade the RNA

Nature Chemical Biology, 2023
openaire   +2 more sources

RNA-degrading activities in chicken liver

Biosystems, 1972
Abstract The occurrence, intra-cellular distribution and properties of ribonucleases in chicken liver were investigated. The pH-activity curve obtained with chicken liver cell-free preparation showed two pH optima, one at pH 5.0 and the other at pH 9.5. A considerable hydrolysis of RNA (yeast) over the pH range 7.0 to 9.0 was also observed.
openaire   +2 more sources

Eukaryotic messenger RNA degradation

BioEssays, 1988
N, van Belzen   +2 more
openaire   +2 more sources

The effect of environmental conditions on the rate of RNA degradation in dried blood stains

Forensic Science International: Genetics, 2021
Jane Pritchard   +2 more
exaly  

Methods for detecting RNA degradation intermediates in plants

Plant Science, 2022
Daishin Ueno, Shotaro Yamasaki
exaly  

New progresses of circular RNA biology: from nuclear export to degradation

RNA Biology, 2021
Min Zhou, Zhengguo Li, Mei-Sheng Xiao
exaly  

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