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DEGRADATION OF MESSENGER RNA IN MAMMALIAN CELLS
Acta Endocrinologica, 1972ABSTRACT Analyses of the response of hydrocortisone-induced tyrosine transaminase in cultured H-35 cells to inhibitors of translation (cycloheximide, puromycin) suggest: (1) that bound ribosomes stabilize messenger RNA in vivo; (2) that messenger is degraded at a rate determined by the rate of translation.
F T, Kenney, K L, Lee, C D, Stiles
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Structural organization of the RNA-degrading exosome
Current Opinion in Structural Biology, 2008The RNA exosome participates in the degradation and processing of a wide range of RNA molecules. Recent advances in understanding how the exosome is organized and functions largely stem from structural studies. Crystal structures of archaeal exosomes bound to RNA and of the corresponding nine-subunit human exosome core show that the archaeal and ...
Lorentzen, E.; id_orcid 0000-0001-6493-7220 +2 more
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RNA and protein degradation in the aging process
Cellular SignallingAging involves a profound reorganization of metabolic processes, marked by a progressive decline in anabolic activity and a compensatory increase in catabolic flux. This imbalance drives cellular dysfunction and contributes to age-related phenotypes, including sarcopenia, anorexia, and sleep disturbances.
Junqiang, Lin +7 more
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RNA-degrading activities in chicken liver
Biosystems, 1972Abstract The occurrence, intra-cellular distribution and properties of ribonucleases in chicken liver were investigated. The pH-activity curve obtained with chicken liver cell-free preparation showed two pH optima, one at pH 5.0 and the other at pH 9.5. A considerable hydrolysis of RNA (yeast) over the pH range 7.0 to 9.0 was also observed.
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The effect of environmental conditions on the rate of RNA degradation in dried blood stains
Forensic Science International: Genetics, 2021Jane Pritchard +2 more
exaly
Methods for detecting RNA degradation intermediates in plants
Plant Science, 2022Daishin Ueno, Shotaro Yamasaki
exaly
New progresses of circular RNA biology: from nuclear export to degradation
RNA Biology, 2021Min Zhou, Zhengguo Li, Mei-Sheng Xiao
exaly

