Results 291 to 300 of about 5,666,730 (325)
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Ultracentrifuge studies of RNA degradation
Archives of Biochemistry and Biophysics, 1962Ultracentrifuge studies of RNA from Ehrlich ascites cells have shown that the original 28, 18, and 3–5 S components change progressively as a result of degradation. The 28 S component diminishes at a much more rapid rate than the 18 S, and their relative ratio changes as a function of the age of the RNA samples. Intermediary components of 24, 21, 15,
J, HUPPERT, J, PELMONT
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On the degradation of intracellular RNA by ribonucleases
International Journal of Biochemistry, 1986The kinetic and the specificity of two RNases purified from the insect. C. capitata have been studied. These two enzymes exhibit preference to degrade large polynucleotides. The alkaline enzyme is located in the soluble cellular fraction and the acid enzyme is also associated to microsomes and lysosomes.
Jvan M. Garcia-Segura +4 more
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Polyadenylation and degradation of RNA in the mitochondria
Biochemical Society Transactions, 2016Mitochondria have their own gene expression machinery and the relative abundance of RNA products in these organelles in animals is mostly dictated by their rate of degradation. The molecular mechanisms regulating the differential accumulation of the transcripts in this organelle remain largely elusive.
Shiri, Levy, Gadi, Schuster
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Maturation and degradation of RNA in bacteria
Current Opinion in Microbiology, 2007RNA decay plays an important role, not only in recycling nucleotides but also in determining the rapidity with which cells can react to changing growth conditions. The degradation process can be regulated, thus providing an often-underestimated means of controlling gene expression. Recent developments in the field of RNA maturation and decay in two key
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Degradation of circular RNA by the ribonuclease DIS3
Molecular CellFeatures of circular RNAs (circRNAs) produced by back-splicing of eukaryotic exon(s) make them resistant to degradation by linear RNA decay machineries. Thus, a general circRNA degradation pathway under normal conditions has remained largely elusive.
Ling-Ling Chen +2 more
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Messenger RNA degradation in Saccharomyces cerevisiae
Gene, 1988The analysis of 17 functional mRNAs and two recombinant mRNAs in the yeast Saccharomyces cerevisiae suggests that the length of an mRNA influences its half-life in this organism. The mRNAs are clearly divisible into two populations when their lengths and half-lives are compared.
A J, Brown +5 more
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Direction of in vivo Degradation of a Messenger RNA
Nature, 1968Degradation begins at the 3′ end of a trp, mRNA molecule and progresses sequentially to the 5′ end.
R F, Baker, C, Yanofsky
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High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects
bioRxiv, 2021Huawei Tong +22 more
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Degradation of RNA in Escherichia coli
Molecular and General Genetics MGG, 1973A hypothesis to explain RNA degradation in Escherichia coli is proposed. In this hypothesis all classes of RNA are potentially degradable unless they are protected. The proposed mechanism for mRNA degradation requires a combination of endonuclease(s) and exonuclease(s) which degrades RNA in the 3′ to 5′ direction.
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Linking circular intronic RNA degradation and function in transcription by RNase H1
Science China Life Sciences, 2021Xiang Li +11 more
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