Results 151 to 160 of about 2,110,017 (419)
Strand displacement: a fundamental mechanism in RNA biology? [PDF]
arXiv, 2019 DNA and RNA are generally regarded as central molecules in molecular biology. Recent advancements in the field of DNA/RNA nanotechnology successfully used DNA/RNA as programmable molecules to construct molecular machines and nanostructures with predefined shapes and functions.
arxiv
Communications Biology, 2019 RNA editing converting cytidines into uridines is a hallmark of gene expression in land plant chloroplasts and mitochondria. Pentatricopeptide repeat (PPR) proteins have a key role in target recognition, but the functional editosome in the plant ...
Bastian Oldenkott +4 more
semanticscholar +1 more source
Comparative RNA editing in autistic and neurotypical cerebella [PDF]
, 2012 Adenosine-to-inosine (A-to-I) RNA editing is a neurodevelopmentally regulated epigenetic modification shown to modulate complex behavior in animals.
Brown, Emery N. +11 more
core +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
A new distance for high level RNA secondary structure comparison [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics
2 (2005) 3--14, 2008 We describe an algorithm for comparing two RNA secondary structures coded in the form of trees that introduces two new operations, called node fusion and edge fusion, besides the tree edit operations of deletion, insertion, and relabeling classically used in the literature. This allows us to address some serious limitations of the more traditional tree
arxiv
RNA editing underlies genetic risk of common inflammatory diseases
Nature, 2022 Qin Li +11 more
semanticscholar +1 more source
RNA editing in the forefront of epitranscriptomics and human health
Journal of Translational Medicine, 2019 Post-transcriptional modifications have been recently expanded with the addition of RNA editing, which is predominantly mediated by adenosine and cytidine deaminases acting on DNA and RNA.
Theodoulakis Christofi, A. Zaravinos
semanticscholar +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes
Nature Methods, 2021 Chunlong Xu +15 more
semanticscholar +1 more source
RNA editing in nascent RNA affects pre-mRNA splicing
Genome Research, 2018 In eukaryotes, nascent RNA transcripts undergo an intricate series of RNA processing steps to achieve mRNA maturation. RNA editing and alternative splicing are two major RNA processing steps that can introduce significant modifications to the final gene ...
Y. Hsiao +7 more
semanticscholar +1 more source