Results 171 to 180 of about 2,133,969 (419)
RNA editing at a splicing site of NADH dehydrogenase subunit IV gene transcript in wheat mitochondria [PDF]
, 1989 Lorenzo Lamattina +2 more
openalex +1 more source
RNA editing in nascent RNA affects pre-mRNA splicing
Genome Research, 2018 In eukaryotes, nascent RNA transcripts undergo an intricate series of RNA processing steps to achieve mRNA maturation. RNA editing and alternative splicing are two major RNA processing steps that can introduce significant modifications to the final gene ...
Y. Hsiao +7 more
semanticscholar +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. [PDF]
, 1994 Uh‐Hyun Kim +4 more
openalex +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
RNA editing by G-nucleotide insertion in mumps virus P-gene mRNA transcripts [PDF]
, 1990 Reay G. Paterson, Robert A. Lamb
openalex +1 more source
RNA editing of Filamin A pre‐mRNA regulates vascular contraction and diastolic blood pressure
EMBO Journal, 2018 Epitranscriptomic events such as adenosine‐to‐inosine (A‐to‐I) RNA editing by ADAR can recode mRNAs to translate novel proteins. Editing of the mRNA that encodes actin crosslinking protein Filamin A (FLNA) mediates a Q‐to‐R transition in the interactive ...
M. Jain +23 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons
Cell Reports, 2020 Summary: Adenosine-to-inosine RNA editing, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, alters RNA sequences from those encoded by DNA. These editing events are dynamically regulated, but few trans regulators of ADARs are known in vivo.
Anne L. Sapiro +8 more
doaj
AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer.
JCI Insight, 2018 Adenosine-to-inosine (A-to-I) RNA editing, a process mediated by adenosine deaminases that act on the RNA (ADAR) gene family, is a recently discovered epigenetic modification dysregulated in human cancers.
K. Shigeyasu +12 more
semanticscholar +1 more source