Results 171 to 180 of about 685,668 (343)

Highly specific chimeric DNA-RNA guided genome editing with enhanced CRISPR-Cas12a system [PDF]

, 2021
Hanseop Kim, Wi-jae Lee, Chan Hyoung Kim, Yeounsun Oh, Lee Wha Gwon, Hyomin Lee, Woojeung Song, Junho K. Hur, Kyung‐Seob Lim, Kang Jin Jeong, Ki‐Hoan Nam, Young‐Suk Won, Youngjeon Lee, Younghyun Kim, Jae‐Won Huh, Bong‐Hyun Jun, Dong‐Seok Lee, Seung Hwan Lee   +17 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Additional file 3: of Evolutionarily significant A-to-I RNA editing events originated through G-to-A mutations in primates

, 2019
Ni An, Wanqiu Ding, Xinzhuang Yang, Jiguang Peng, Bin He, Qing Shen, Fujian Lu, Aibin He, Yong Zhang, Bertrand Chin‐Ming Tan, Jiayu Chen, Chuan‐Yun Li   +11 more
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

MOESM1 of ADAR1-mediated RNA-editing of 3′UTRs in breast cancer

, 2018
Eduardo A. Sagredo, Alejandro Blanco, Alfredo Sagredo, Paola Pérez, Gonzalo Sepúlveda-Hermosilla, Fernanda Morales, Bettina Müller, Ricardo A. Verdugo, Katherine Marcelain, Olivier Harismendy, Ricardo Armisén   +10 more
openalex   +1 more source

A-to-I RNA editing and cancer: From pathology to basic science [PDF]

, 2008
Angela Gallo, Silvia Galardi
openalex   +1 more source

Genome-Wide Analysis on Driver and Passenger RNA Editing Sites Suggests an Underestimation of Adaptive Signals in Insects [PDF]

, 2023
Yuchen Zhang, Yuange Duan
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Plastid signalling under multiple conditions is accompanied by a common defect in RNA editing in plastids [PDF]

, 2011
Tomohiro Kakizaki, Fumiko Yazu, Katsuhiro Nakayama, Yasuko Ito‐Inaba, Takehito Inaba   +4 more
openalex   +1 more source