Results 231 to 240 of about 1,495,760 (258)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Target-stabilized base editors enable robust high-fidelity RNA editing. [PDF]

Nat Commun
Liu T, Lin Y, Liu Q, Liao W, Lin Y, Zhang Y, Zhang J, Cao W, Yang L, Hong Z, Lu Z.   +10 more
europepmc   +1 more source

Mitochondrial genome of the invasive weed Amaranthus palmeri: structural features, RNA editing, and evolutionary insights. [PDF]

BMC Plant Biol
Zheng J, Bai X, Zhu T, Li A, Yan J, Li H, Qi Z, Dai S, Yan X.   +8 more
europepmc   +1 more source

ADAR1 and ADAR2 Expression in the Thoracic Aortic Wall Correlates with Aneurysm Severity and Dissection Risk: Insights into A-to-I RNA Editing Dysregulation in Marfan Syndrome-Derived vSMCs. [PDF]

Int J Mol Sci
Pisano C, Colopi A, Silvestris DA, Terriaca S, Guida E, Porreca A, Sbrigata A, Doronzio PN, Orlandi A, Dolci S, La Rosa P, Cesarini V.   +11 more
europepmc   +1 more source

ADAR1-Mediated RNA Editing Regulates Innate Immunity in Pulmonary Hypertension. [PDF]

Circ Res
Shen Y, Bisserier M.
europepmc   +1 more source

Adaptive Spo11 RNA editing gate optimizes meiosis I pace and mitotic proliferation while preserving ascospore formation. [PDF]

Sci Adv
Wu M, Liu J, Han J, Huang J, Feng C, Jiang C, Xu JR, Wang Q, Liu H.   +8 more
europepmc   +1 more source

In vivo chemogenetic RNA editing of macrophages by bioengineered viruses for sepsis treatment. [PDF]

Nat Commun
Xi W, Xu Y, Bao W, Ding Z, Xiao H, Yang J, Yan X, Ping Y.   +7 more
europepmc   +1 more source

Conditional production of RNA hairpins in mammalian cells.

, 2003
TocchiniValentini GP Conditional production of RNA hairpins in mammalian cells, Deidda G, Calandra P, Mannironi C   +3 more
core  

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A-to-I editing prevents self-RNA sensing

Nature Reviews Molecular Cell Biology, 2022
Leilei Chen
exaly  

Temperature-dependent RNA editing in octopus extensively recodes the neural proteome

Cell, 2023
Joshua J C Rosenthal
exaly