Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system [PDF]
, 2013 The fine control of molecules mediating communication in the nervous system is key to adjusting neuronal signaling during development and in maintaining the stability of established networks in the face of altered sensory input.
Ales eBalik +3 more
core +2 more sources
Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples
Frontiers in Genetics, 2019 RNA editing is phenomenon that occurs in both protein coding and non-coding RNAs. Increasing evidence have shown that adenosine-to-inosine RNA editing can potentially rendering substantial functional effects throughout the genome.
Michael Chigaev +8 more
doaj +1 more source
A-to-I RNA Editing in Cancer: From Evaluating the Editing Level to Exploring the Editing Effects
Frontiers in Oncology, 2021 As an important regulatory mechanism at the posttranscriptional level in metazoans, adenosine deaminase acting on RNA (ADAR)-induced A-to-I RNA editing modification of double-stranded RNA has been widely detected and reported.
Heming Wang +9 more
doaj +1 more source
Universal RNA editing in a human liver at the fetal stage [PDF]
, 2012 It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, rRNA,
Chen, Huiping +4 more
core +1 more source
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
, 2020 Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A +5 more
core +3 more sources
RNA editing generates cellular subsets with diverse sequence within populations [PDF]
, 2016 RNA editing is a mutational mechanism that specifically alters the nucleotide content in transcribed RNA. However, editing rates vary widely, and could result from equivalent editing amongst individual cells, or represent an average of variable editing ...
Harjanto, D. +5 more
core +1 more source
RNA Editing in Chloroplasts of Spirodela polyrhiza, an Aquatic Monocotelydonous Species. [PDF]
PLoS ONE, 2015 RNA editing is the post-transcriptional conversion from C to U before translation, providing a unique feature in the regulation of gene expression.
Wenqin Wang +4 more
doaj +1 more source
RNA Editing and Its Roles in Plant Organelles
Frontiers in Genetics, 2021 RNA editing, a vital supplement to the central dogma, yields genetic information on RNA products that are different from their DNA templates. The conversion of C-to-U in mitochondria and plastids is the main kind of RNA editing in plants. Various factors
Wei Hao +12 more
doaj +1 more source
Evolution of substrate-specific gene expression and RNA editing in brown rot wood-decaying fungi. [PDF]
, 2019 Fungi that decay wood have characteristic associations with certain tree species, but the mechanistic bases for these associations are poorly understood.
Ahrendt, Steven +10 more
core +1 more source
Four related proteins of the Trypanosoma brucei RNA editing complex [PDF]
, 2001 RNA editing in kinetoplastid mitochondria occurs by a series of enzymatic steps that is catalyzed by a macromolecular complex. Four novel proteins and their corresponding genes were identified by mass spectrometric analysis of purified editing complexes ...
Aebersold, R +10 more
core +1 more source