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Protein-facilitated RNA folding
Current Opinion in Structural Biology, 1997In the absence of protein collaborators, both simple and complex RNAs often misfold or are unfolded. Biologically important RNAs solve their folding problem, in part, using the assistance of chaperone and cofactor proteins. Recent work emphasizes several rules for RNA-protein complexes: formation involves induced fit; many large RNAs fold slowly; and ...
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Monte Carlo Inverse RNA Folding
The inverse RNA folding problem deals with designing a sequence of nucleotides that will fold into a desired target structure. Generalized Nested Rollout Policy Adaptation (GNRPA) is a Monte Carlo search algorithm for optimizing a sequence of choices. It learns a playout policy to intensify the search of the state space near the current best sequence ...Tristan, Cazenave, Hamza, Touzani
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RNA Folding, Mutation, and Detection
The structure of RNA molecules is absolutely critical to their functions in a biological system. RNA structure is dynamic and changes in response to cellular needs. Within the last few decades, there has been an increased interest in studying the structure of RNA molecules and how they change to support the needs of the cell in different conditions ...Kaitlin E, Klotz, Kausik, Chakrabarti
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The Folding Landscapes of Human Telomeric RNA and DNA GâQuadruplexes are Markedly Different
Angewandte Chemie - International Edition, 2021Irene Bessi +2 more
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High-Throughput Investigation of Diverse Junction Elements in RNA Tertiary Folding
Cell, 2018Namita Bisaria +2 more
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The Biogenesis of SRP RNA Is Modulated by an RNA Folding Intermediate Attained during Transcription
Molecular Cell, 2020Shingo Fukuda +2 more
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Multiple native states reveal persistent ruggedness of an RNA folding landscape
Nature, 2010Daniel Herschlag
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RNA Hairpin Folding in the Crowded Cell
Angewandte Chemie - International Edition, 2016Mimi Gao +2 more
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