Results 251 to 260 of about 125,592 (278)

Discovery of Thermal Sensitizers That Inhibit Heat-Induced SAFB Granule Formation. [PDF]

J Med Chem
Furutani Y, Shimasaki N, Yamada R, Ohtsuki T, Watanabe K.   +4 more
europepmc   +1 more source

Safety and Effectiveness of Glecaprevir/Pibrentasvir in Children and Adolescents With Chronic Hepatitis C: Reports From All‐Case Post‐Marketing Surveillance in Japan

Hepatology Research, EarlyView.
ABSTRACT Aim The aim of this all‐case post‐marketing study was to evaluate the real‐world safety and effectiveness in all children and adolescents with chronic hepatitis C with or without compensated cirrhosis treated with glecaprevir/pibrentasvir (G/P) in Japan. Methods This prospective, observational post‐marketing surveillance study was conducted at
Tatsuki Mizuochi, Katsuyoshi Kawana, Mariko Kobayashi, Eri Iwashita, Itaru Iwama, Daiki Abukawa, Hitoshi Tajiri   +6 more
wiley   +1 more source

A genetic interaction between DED1 and HAT1 in Saccharomyces cerevisiae reveals a role for Hat1p in cytoplasmic RNA granule accumulation. [PDF]

G3 (Bethesda)
Panko AJ, Winters A, Rothbard NR, Hilliker AK.   +3 more
europepmc   +1 more source

Aub, Vasa, and Armi concentration in phase-separated nuage is dispensable for piRNA biogenesis and transposon silencing. [PDF]

RNA
Ho S, Rice NP, Yu T, Weng Z, Theurkauf WE.   +4 more
europepmc   +1 more source

FUS is an N1- and N6-methyladenosine-binding protein. [PDF]

Nucleic Acids Res
Liang X, Zhao T, Dai X, Sun Y, Yuan J, Afzalpurkar S, Duong C, Yu A, Tang F, He X, Liu X, Chen X, Cao Z, Wang Y.   +13 more
europepmc   +1 more source

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RNA granules in neuronal plasticity and disease

Trends in Neurosciences, 2023
RNA granules are dynamic entities controlling the spatiotemporal distribution and translation of RNA molecules. In neurons, a variety of RNA granules exist both in the soma and in cellular processes. They contain transcripts encoding signaling and synaptic proteins as well as RNA-binding proteins causally linked to several neurological disorders.
Karl E. Bauer, Bruna R. de Queiroz, Michael A. Kiebler, Florence Besse   +3 more
openaire   +2 more sources

RNA granules and cytoskeletal links

Biochemical Society Transactions, 2014
In eukaryotic cells, non-translating mRNAs can accumulate into cytoplasmic mRNP (messenger ribonucleoprotein) granules such as P-bodies (processing bodies) and SGs (stress granules). P-bodies contain the mRNA decay and translational repression machineries and are ubiquitously expressed in mammalian cells and lower eukaryote species including ...
Rajgor, Dipen, Shanahan, Catherine M.
openaire   +3 more sources

RNA Granule Organization

The FASEB Journal, 2017
Germ granules, specialized ribonucleoprotein particles, are a hallmark of all germ cells. In Drosophila , an estimated 200 mRNAs are enriched in the germ plasm, and some of these have important, often conserved roles in germ cell formation, specification, survival and migration. How mRNAs are
Ruth Lehmann, Tatjana Trcek, Markus Grosch, Hari Shroff, Timothée Lionnet   +4 more
openaire   +1 more source

Stress granules: the Tao of RNA triage

Trends in Biochemical Sciences, 2008
Cytoplasmic RNA structures such as stress granules (SGs) and processing bodies (PBs) are functional byproducts of mRNA metabolism, sharing substrate mRNA, dynamic properties and many proteins, but also housing separate components and performing independent functions.
Paul, Anderson, Nancy, Kedersha
openaire   +2 more sources

Cytoplasmic RNA granules, ribostasis, and neurodegeneration

Neurology, 2018
The regulation of translation and decay of messenger RNA (mRNA) is a key mechanism for control of gene expression. During transcription in the nucleus, nascent mRNAs assemble with a set of RNA-binding proteins to form messenger ribonucleoprotein particles (mRNPs).
openaire   +2 more sources