RNA helicase and colon cancer [PDF]
Cancer Biology & Therapy, 2008 Commentary to:Knockdown of RCK/p54 expression by RNAi inhibits proliferation of human colorectal cancer cells in vitro and in vivo Fang Lin, Rui Wang, Jian-Jun Shen, Xi Wang, Ping Gao, Ke Dong, Hui-Zhong ...
Jun, Zhang +3 more
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RNA Helicase A Regulates the Replication of RNA Viruses [PDF]
Viruses, 2021 The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview
Rui-Zhu Shi, Yuan-Qing Pan, Li Xing
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The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis [PDF]
, 2019 Post-transcriptional mechanisms have the potential to influence complex changes in gene expression, yet their role in cell fate transitions remains largely unexplored.
Aigner, S. +21 more
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Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs. [PDF]
, 2017 Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals.
Gina Broitman-Maduro +10 more
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Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer [PDF]
, 2017 Purpose: DEAD box protein 3 (DDX3) is an RNA helicase with oncogenic properties that shuttles between the cytoplasm and nucleus. The majority of DDX3 is found in the cytoplasm, but a subset of tumors has distinct nuclear DDX3 localization of yet unknown ...
Bol, Guus M. +10 more
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DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation. [PDF]
PLoS Pathogens, 2014 RIG-I is a DExD/H-box RNA helicase and functions as a critical cytoplasmic sensor for RNA viruses to initiate antiviral interferon (IFN) responses. Here we demonstrate that another DExD/H-box RNA helicase DHX36 is a key molecule for RIG-I signaling by ...
Ji-Seung Yoo +12 more
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Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity [PDF]
, 2004 We report the transcriptional response of Escherichia coli MG1655 to damage induced by colicins E3 and E9, bacteriocins that kill cells through inactivation of the ribosome and degradation of chromosomal DNA, respectively. Colicin E9 strongly induced the
Hinton, Jay C. D. +6 more
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RNA Strand Displacement Assay for Hepatitis E Virus Helicase
Bio-Protocol, 2017 The hepatitis E virus (HEV) helicase uses ATP to unwind the RNA duplexes. This is an essential step for viral replication. This protocol aims to measure the double strand RNA unwinding activity of the HEV helicase.
Vidya Nair, Milan Surjit
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, 2013 EC number 3.6.4.13 Systematic name ATP phosphohydrolase (RNA helix unwinding) Recommended name RNA helicase Synonyms 1a NTPase/helicase [5] ATP/dATP-dependent RNA helicase [32] ATPase [1,36] ATPase/RNA helicase [32] ATPase/helicase [36,41] BMV 1a protein [5] BmL3-helicase [32] Brr2p [50] DBP2 [30] DDX17 [12] DDX19 [56] DDX25 [
Schomburg, Dietmar, Schomburg, Ida
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Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing [PDF]
Nucleic Acids Research, 2014 Helicases contribute to diverse biological processes including replication, transcription and translation. Recent reports suggest that unwinding of some helicases display repetitive activity, yet the functional role of the repetitiveness requires further investigation.
Koh, Hye Ran +3 more
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