Results 131 to 140 of about 342,007 (314)

Single molecule experiments in biophysics: exploring the thermal behavior of nonequilibrium small systems

, 2005
Biomolecules carry out very specialized tasks inside the cell where energies involved are few tens of k_BT, small enough for thermal fluctuations to be relevant in many biomolecular processes.
B Onoa, C Jarzynski, D Evans, D M Zuckerman, E Fermi, F Ritort, F Ritort, F. Ritort, G E Crooks, G M Wang, J Gore, J Liphardt, J Liphardt, P Cluzel, S B Smith, S B Smith, S B Smith, S Cocco, S Park, T R Strick, W R Loewenstein   +20 more
core   +2 more sources

The function and architecture of DEAH/RHA helicases

Biomolecular Concepts, 2011
Helicases are ubiquitous enzymes that participate in every aspect of nucleic acid metabolism. The DEAH/RHA family of helicases are involved in a variety of cellular processes including transcriptional and translational regulation, pre-mRNA splicing, pre ...
He Yangzi, Andersen Gregers R., Nielsen Klaus H.   +2 more
doaj   +1 more source

Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants

Advanced Science, EarlyView.
The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley   +1 more source

Human RNA helicase A is a lupus autoantigen that is cleaved during apoptosis.

Journal of Immunology, 1999
Proteolytic cleavage by caspases is the central event in cells undergoing apoptosis. Cleaved proteins are often targeted by autoantibodies, suggesting that the cleavage of self Ags enhances immunogenicity and is prone to induce an autoimmune response. We
Yoshihiko Takeda, Patricia Caudell, Giuia Grady, Grace Wang, Akira Suwa, Gordon C. Sharp, W. Dynan, John A. Hardin   +7 more
semanticscholar   +1 more source

Transcriptional changes in trichothiodystrophy cells [PDF]

, 2008
Mutations in three of the genes encoding the XPB, XPD and TTDA components of transcription factor TFIIH can result in the clinical phenotype of trichothiodystrophy (TTD).
Alan Lehmann, Bergmann, Boerma, Bootsma, Botta, Broughton, Coin, Coin, Compe, Compe, da Costa, de Boer, de Boer, Doniger, Drane, Drapkin, Dubaele, Giglia-Mari, Hohl, Hosack, Itin, Jacky Pallas, Judith Offman, Keriel, Koch-Paiz, Kraemer, Kraemer, Lee, Lehmann, Lehmann, Lehmann, Mike Hubank, Nakabayashi, Nipurna Jina, Park, Pemble, Ranish, Reardon, Schaeffer, Selzer, Sesto, Smyth, Storey, Taylor, Therina Theron, Viprakasit, Wu   +46 more
core   +2 more sources

Role of DEAD-box RNA helicase genes in the growth of Yersinia pseudotuberculosis IP32953 under cold, pH, osmotic, ethanol and oxidative stresses.

PLoS ONE, 2019
Yersinia pseudotuberculosis is an important foodborne pathogen threatening modern food safety due to its ability to survive and grow at low temperatures. DEAD-box RNA helicase CsdA has been shown to play an important role in the low-temperature growth of
Xiaojie Jiang, Riikka Keto-Timonen, Mikael Skurnik, Hannu Korkeala   +3 more
doaj   +1 more source

RNA Helicase Mediates Competitive Fitness of Listeria monocytogenes on the Surface of Cantaloupe

Horticulturae, 2018
Listeria monocytogenes is a foodborne pathogen that is implicated in numerous outbreaks of disease (listeriosis) via fresh produce. The genetic features of L. monocytogenes that allow adherence and growth on produce remain largely uncharacterized.
Robert Price, Cameron Parsons, Sophia Kathariou   +2 more
doaj   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells

Nature Cell Biology, 2020
The availability of nucleotides has a direct impact on transcription. The inhibition of dihydroorotate dehydrogenase (DHODH) with leflunomide impacts nucleotide pools by reducing pyrimidine levels.
C. Santoriello, Audrey Sporrij, Song Yang, Ryan A. Flynn, Telmo Henriques, Bilguujin Dorjsuren, Eugenia Custo Greig, Wyatt McCall, Meredith E. Stanhope, Maurizio Fazio, M. Superdock, Asher E Lichtig, Isaac Adatto, B. Abraham, Marian Kalocsay, Michael Jurynec, Yi Zhou, K. Adelman, Eliezer Calo, L. Zon   +19 more
semanticscholar   +1 more source

Multiple Functions of Nuclear DNA Helicase II (RNA Helicase A) in Nucleic Acid Metabolism

Acta Biochimica et Biophysica Sinica, 2004
Nuclear DNA helicase II (NDH II), or RNA helicase A (RHA), was initially discovered in mammals by conventional protein purification methods. Molecular cloning identified apparent sequence homologies between NDH II and a Drosophila protein named maleless (MLE), the latter being essential for the Drosophila X-chromosome dosage compensation.
Suisheng, Zhang, Frank, Grosse
openaire   +2 more sources