Results 181 to 190 of about 125,618 (325)

Transcription‐coupled repair: tangled up in convoluted repair

open access: yesThe FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher   +3 more
wiley   +1 more source

Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock

open access: yesThe FEBS Journal, EarlyView.
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány   +6 more
wiley   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

open access: yesThe FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak   +7 more
wiley   +1 more source

Leukophysin: an RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles. [PDF]

open access: bronze, 1996
Mohamed Abdelhaleem   +3 more
openalex   +1 more source

Ras pathways help buffer biological timekeeping against metabolic perturbations

open access: yesThe FEBS Journal, EarlyView.
Circadian clocks must be buffered (compensated) against conditions that could affect their rate (period). This figure shows rhythmic peaks of spore formation driven by the clock of the fungus Neurospora: The period is the same under different nutritional conditions in the wild‐type but not in a RasGEF mutant that disrupts an intracellular signaling ...
Patricia Lakin‐Thomas
wiley   +1 more source

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