Results 201 to 210 of about 342,007 (314)

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

The RNA helicase eIF4A as a novel target in insect cells to combat arboviral infections. [PDF]

PLoS One
Rehling T, Mentchen K, Konopka L, Obermann W, Weber F, Schmerer P, Schetelig MF, Grünweller A, Häcker I, Magari F.   +9 more
europepmc   +1 more source

Autoantikörper gegen RNA-Helicase A [PDF]

, 2019
openaire   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.

European Journal of Biochemistry, 2004
T. Tetsuka, Hiroaki Uranishi, T. Sanda, K. Asamitsu, Jiang Yang, F. Wong-Staal, T. Okamoto   +6 more
semanticscholar   +1 more source

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

Insect Molecular Biology, Volume 35, Issue 3, Page 217-231, June 2026.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin, Szu‐Chieh Wang, Charles E. Cook, Ming‐Der Lin, Chun‐che Chang   +4 more
wiley   +1 more source

RNA helicase SKIV2L impedes tumor immunity by reprogramming arginine metabolism of hepatocellular carcinomas. [PDF]

J Immunother Cancer
Zhu L, Wu M, Feng B, Zhang Y, Xu Y, Yu L.   +5 more
europepmc   +1 more source

A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.

RNA: A publication of the RNA Society, 2012
Zarko Manojlovic, B. Stefanovic
semanticscholar   +1 more source

Affinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in Plants

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter, Verena Gaugler, Sara Christina Stolze, Riya Ghosh, Akhila Jayamon, Ranjana Yadav, Felix Wollensack, Debabrata Laha, Hirofumi Nakagami, Gabriel Schaaf, Henning Jacob Jessen   +10 more
wiley   +1 more source

Identification and optimization of first-in-class RNA helicase inhibitors of DDX1, LGP2, and MDA5. [PDF]

Eur J Med Chem
Wang X, Wang F, Kong D, Uredi D, Li F, Li F, Rayadurgam J, Li H, Wolf E, Chan UH, Chau I, Zeng H, Perez JG, Wilson DJ, Bashore FM, Wang X, Halabelian L, Frankowski KJ, Kireev D, Axtman AD.   +19 more
europepmc   +1 more source