Results 261 to 270 of about 92,282 (271)
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Pre-mRNA and mRNA binding of human nuclear DNA helicase II (RNA helicase A)
Journal of Cell Science, 1999ABSTRACT Nuclear DNA helicase II (NDH II), alternatively named RNA helicase A, seems to function as a pre-mRNA and mRNA binding protein in human cells. Immunofluorescence studies of NDH II gave a highly diffused nucleoplasmic staining that was similar to that of hnRNP A1 but differed from the localization of the RNA splicing factor Sc-35.
S, Zhang, C, Herrmann, F, Grosse
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Solution structures of the double‐stranded RNA‐binding domains from rna helicase A
Proteins: Structure, Function, and Bioinformatics, 2012AbstractRNA helicase A (RHA) is a highly conserved protein with multifaceted functions in the gene expression of cellular and viral mRNAs. RHA recognizes highly structured nucleotides and catalytically rearranges the various interactions between RNA, DNA, and protein molecules to provide a platform for the ribonucleoprotein complex.
Takashi, Nagata +7 more
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Active Disruption of an RNA-Protein Interaction by a DExH/D RNA Helicase
Science, 2001All aspects of cellular RNA metabolism and the replication of many viruses require DExH/D proteins that manipulate RNA in a manner that requires nucleoside triphosphates. Although DExH/D proteins have been shown to unwind purified RNA duplexes, most RNA molecules in the cellular environment are complexed with proteins.
E, Jankowsky +3 more
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A Novel Human Homolog of a Dead-Box RNA Helicase Family
Biochemical and Biophysical Research Communications, 1994Putative cDNA clones for a nuclear antigen that cross-reacts with anti-human aldolase A monoclonal antibody MAb1A2 were isolated from the HeLa lambda gt11 cDNA library and a candidate clone (clone 3) was analyzed. The cDNA has an open reading frame (ORF) of 1,317 bp encoding a novel RNA helicase belonging to the DEAD RNA helicase family.
Y, Kitajima +4 more
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Escherichia coli DbpA Is a 3‘ → 5‘ RNA Helicase
Biochemistry, 2005Previous work has demonstrated that Escherichia coli DbpA is a nonprocessive RNA helicase that can disrupt short RNA helices on either the 5' side or 3' side of hairpin 92 of 23S rRNA. Here the directionality of the helicase activity of DbpA was determined by using substrates containing a short reporter helix in the presence of a second adjacent helix ...
Camille M, Diges, Olke C, Uhlenbeck
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Oncoprotein EWS-FLI1 Activity Is Enhanced by RNA Helicase A
Cancer Research, 2006Abstract RNA helicase A (RHA), a member of the DEXH box helicase family of proteins, is an integral component of protein complexes that regulate transcription and splicing. The EWS-FLI1 oncoprotein is expressed as a result of the chromosomal translocation t(11;22) that occurs in patients with the Ewing's sarcoma family of tumors (ESFT ...
Jeffrey A, Toretsky +8 more
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Identification of a Differentially Expressed RNA Helicase by Gene Trapping
Biochemical and Biophysical Research Communications, 1999A mouse line was generated that expressed a gene trap reporter construct, betageo, in a dynamic pattern during embryonic development. Differential expression was seen within the developing eyes, limbs, heart, neural tube, and skeleton. Two transcripts were cloned that contained endogenous sequences fused to the gene trap vector sequence.
D S, Wagner, L, Gan, W H, Klein
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