Results 261 to 270 of about 2,074,197 (379)

Bax Inhibitor-1 Is Overexpressed in Prostate Cancer and Its Specific Down-Regulation by RNA Interference Leads to Cell Death in Human Prostate Carcinoma Cells [PDF]

, 2003
Michal Grzmil, Paul Thelen, Bernhard Hemmerlein, Stefan Schweyer, Silke Voigt, Dina Mury, Peter Burfeind   +6 more
openalex   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Asparaginase and isoaspartyl peptidase 1 RNA interference suppresses the growth of nasopharyngeal carcinoma cells. [PDF]

Discov Oncol
Feng B, Pei Y, Zhang W, Zheng Q, Zhou Y.
europepmc   +1 more source

Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells [PDF]

, 2003
J. Matthew Velkey, K. Sue O’Shea
openalex   +1 more source

Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways

Science, 2013
Arne Weiberg, Ming Wang, F. Lin, Hongwei Zhao, Zhihong Zhang, I. Kaloshian, Hsien-Da Huang, Hailing Jin   +7 more
semanticscholar   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

The efficacy and safety of RNA interference for the treatment of primary hyperoxaluria: a systematic review and meta-analysis. [PDF]

Clin Kidney J
Yu H, Zhong H, Liu Y, Zhang G.
europepmc   +1 more source

RNA Interference Prevents Autosomal-Dominant Hearing Loss

American Journal of Human Genetics, 2016
S. B. Shibata, Paul T. Ranum, Hideaki Moteki, B. Pan, Alexander T. Goodwin, S. Goodman, P. Abbas, J. R. Holt, Richard J. H. Smith   +8 more
semanticscholar   +1 more source

Antioxidant and Anti‐Senescence Polyvinyl Alcohol‐Gallic Acid Supramolecular Hydrogels for Stem Cell Culture

Advanced Healthcare Materials, EarlyView.
The PVA‐GA hydrogel is formed through hydrogen bonding between PVA hydroxyl groups and GA galloyl units, enabling sustainable GA release and its extended biological activity. The hydrogel scavenges ROS to reduce oxidative stress, preventing mitochondrial damage from excessive ROS, mitigating hADSC senescence, and preserving VEGF secretion, offering a ...
Yiduo Zhou, Matías L. Picchio, Yan Nie, Lei Wang, Oihane Sanz, Yue Liu, Xun Xu, Lukas Prantl, Oliver Felthaus, Weiwei Wang, Marcelo Calderón, Nan Ma   +11 more
wiley   +1 more source