Results 261 to 270 of about 508,217 (335)

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source

Investigational RNA Interference Agents for Hepatitis B. [PDF]

BioDrugs
Hui RW, Mak LY, Seto WK, Yuen MF.
europepmc   +1 more source

Mitochondrial uncoupling proteins regulate angiotensin‐converting enzyme expression: crosstalk between cellular and endocrine metabolic regulators suggested by RNA interference and genetic studies

, 2016
Sukhbir Dhamrait, C. Maubaret, Ulrik Pedersen‐Bjergaard, David Brull, Peter Gohlke, John Payne, Michael World, Birger Thorsteinsson, Steve E. Humphries, Hugh Montgomery   +9 more
openalex   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Realizing the therapeutic potential of rapid knockdown of transthyretin via RNA interference in transthyretin amyloidosis. [PDF]

Mol Ther Nucleic Acids
Grogan M, Sheikh FH, Sperry BW, Sweetser MT, Capocelli K, Roblin S, Witteles R.   +6 more
europepmc   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Protocol for RNA interference in gene expression in adult insects of Triatoma infestans (Hemiptera: Reduviidae). [PDF]

STAR Protoc
Córdoba LE, Pérez de Rosas AR, García BA, Stroppa MM.   +3 more
europepmc   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Editor's Note on 'A bi-functional siRNA construct induces RNA interference and also primes PCR amplification for its own quantification'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

RNA Interference Applied to Crustacean Aquaculture. [PDF]

Biomolecules
Fajardo C, De Donato M, Macedo M, Charoonnart P, Saksmerprome V, Yang L, Purton S, Mancera JM, Costas B.   +8 more
europepmc   +1 more source