Results 271 to 280 of about 2,074,197 (379)

Safety and Efficacy of Novel RNA Interference Therapeutic Agent Zilebesiran in People With Hypertension: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Singh V, Tewari J, Qidwai KA, Singh SK, Tewari A, Tewari V, Maheshwari A.   +6 more
europepmc   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

RNA interference protocols for gene silencing in the spittlebug Philaenus spumarius, vector of Xylella fastidiosa. [PDF]

Sci Rep
Parise C, Galetto L, Abbà S, Bodino N, Marzachì C, Bosco D.   +5 more
europepmc   +1 more source

Genetic activation of canonical RNA interference in mice

, 2023
Buccheri V, Pasulka J, Malik R, Loubalova Z, Taborska E, Horvat F, Kulmann MIR, Jenickova I, Prochazka J, Sedlacek R, Svoboda P.   +10 more
europepmc   +1 more source

From guide to target: molecular insights into eukaryotic RNA-interference machinery

Nature Structural &Molecular Biology, 2015
J. J. Ipsaro, L. Joshua-Tor
semanticscholar   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

Advanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han, Godfrey Mwiti, Seo‐Joon Yeom, Jaeyoon Lim, Woo Sik Kim, Sangyong Lim, Seung‐Taik Lim, Eui‐Baek Byun   +7 more
wiley   +1 more source

RNA interference-mediated osteoprotegerin silencing increases the receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio and promotes osteoclastogenesis. [PDF]

World J Stem Cells
Wei SG, Chen HH, Xie LR, Qin Y, Mai YY, Huang LH, Liao HB.   +6 more
europepmc   +1 more source

RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast

, 2002
Ira M. Hall, Ken-ichi Noma, Shiv I. S. Grewal   +2 more
openalex   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Optimized protocols for RNA interference in Macrostomum lignano. [PDF]

G3 (Bethesda)
Mouton S, Mougel A, Ustyantsev K, Dissous C, Melnyk O, Berezikov E, Vicogne J.   +6 more
europepmc   +1 more source