Results 281 to 290 of about 2,074,197 (379)

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

Advanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi, John Cappuccitti   +1 more
wiley   +1 more source

DDX3 participates in miRNA biogenesis and RNA interference through translational control of PACT and interaction with AGO2. [PDF]

FEBS Open Bio
Lai MC, Yu YL, Chen CN, Yu JS, Hung HY, Chan SP.   +5 more
europepmc   +1 more source

RNA Interference Directed against Viral and Cellular Targets Inhibits Human Immunodeficiency Virus Type 1 Replication

, 2002
Rama Mohan Surabhi, Richard B. Gaynor
openalex   +1 more source

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu, Ziwei Pang, Jing Zhao, Jingyi Xue, Hsuan Lo, Tiancheng Gu, Ping Zhang, Jiawei Tian, Guo‐Qing Du   +8 more
wiley   +1 more source

The Evolution and Characterization of the RNA Interference Pathways in Lophotrochozoa. [PDF]

Genome Biol Evol
Formaggioni A, Cavalli G, Hamada M, Sakamoto T, Plazzi F, Passamonti M.   +5 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Beekeepers Support the Use of RNA Interference (RNAi) to Control Varroa destructor. [PDF]

Insects
McGruddy R, Haywood J, Lester PJ.
europepmc   +1 more source

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

Advanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

A Wireless Cortical Surface Implant for Diagnosing and Alleviating Parkinson's Disease Symptoms in Freely Moving Animals

Advanced Healthcare Materials, EarlyView.
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin, Kyungtae Kim, Jaeseung Lee, Johyeon Nam, Eunha Baeg, Chaeyeon You, Hanseul Choi, Minji Kim, Chun Kee Chung, Jae Geun Kim, Jong Hyun Ahn, Miryung Han, Jibum Kim, Sungchil Yang, Sung Q Lee, Sunggu Yang   +15 more
wiley   +1 more source

Broad-scale phenotyping in Arabidopsis reveals varied involvement of RNA interference across diverse plant-microbe interactions. [PDF]

Plant Direct
Ruf A, Thieron H, Nasfi S, Lederer B, Fricke S, Adeshara T, Postma J, Blumenkamp P, Kwon S, Brinkrolf K, Feldbrügge M, Goesmann A, Kehr J, Steinbrenner J, Šečić E, Göhre V, Weiberg A, Kogel KH, Panstruga R, Robatzek S, exRNA consortium.   +20 more
europepmc   +1 more source