Results 291 to 300 of about 2,074,197 (379)

Next-generation libraries for robust RNA interference-based genome-wide screens

Proceedings of the National Academy of Sciences of the United States of America, 2015
M. Kampmann, Max A. Horlbeck, Yuwen Chen, J. Tsai, M. Bassik, Luke A. Gilbert, Jacqueline E. Villalta, S. -. Kwon, Hyeshik Chang, V. Kim, J. Weissman   +10 more
semanticscholar   +1 more source

Nano‐Topography Enhanced Topological‐Cell‐Analysis in Radiation‐Therapy

Advanced Healthcare Materials, EarlyView.
Radiotherapy, a treatment that implies exposition of cells to radiation, offers promise to treat cancer. Here, it is hypothesized that the nanoscale details of a scaffold can amplify the response of cells to radiation, measured through topological variables, providing ways to assess the efficacy of Radiotherapy treatment.
Francesca Pagliari, Maria‐Francesca Spadea, Pierre Montay‐Gruel, Anggraeini Puspitasari‐Kokko, Joao Seco, Luca Tirinato, Angelo Accardo, Francesco De Angelis, Francesco Gentile   +8 more
wiley   +1 more source

Corrigendum to Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer

EBioMedicine
Pinar Kanlikilicer, Recep Bayraktar, Merve Denizli, Mohammed H. Rashed, Cristina Ivan, Burcu Aslan, Rahul Mitra, Kubra Karagoz, Emine Bayraktar, Xinna Zhang, Cristian Rodriguez-Aguayo, Amr Ahmed El-Arabey, Nermin Kahraman, Seyda Baydogan, Ozgur Ozkayar, Michael L. Gatza, Bulent Ozpolat, George A. Calin, Anil K. Sood, Gabriel Lopez-Berestein   +19 more
doaj  

RNA Interference based Midkine Gene Therapy for Hepatocellular Carcinoma. [PDF]

Asian Pac J Cancer Prev
Mamdouh S, Khorshed FEM, Hammad G, Magdy M, Abdelraouf A, Hemida E, Shemis M.   +6 more
europepmc   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference. [PDF]

Nucleic Acids Res
Lobo V, Nowak I, Fernandez C, Correa Muler AI, Westholm JO, Huang HC, Fabrik I, Huynh HT, Shcherbinina E, Poyraz M, Härtlova A, Benhalevy D, Angeletti D, Sarshad AA.   +13 more
europepmc   +1 more source

Optimized protocols for RNA interference inMacrostomum lignano

, 2023
Mouton S, Mougel A, Ustyantsev K, Dissous C, Melnyk O, Berezikov E, Vicogne J.   +6 more
europepmc   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

Advanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou, Johanna Simon, Moritz Beck‐Broichsitter, Gary Davidson, Pavel A. Levkin   +4 more
wiley   +1 more source

Topical RNA Interference Induces Mortality in the Cotton-Melon Aphid <i>Aphis gossypii</i> with No Adverse Effect on the Predator <i>Propylea japonica</i>. [PDF]

Insects
Zhan C, Jiao B, Xu L, Peng Y, Zhao Y.
europepmc   +1 more source