Results 51 to 60 of about 2,276,335 (391)
Evidence For Long-Lasting Transgenerational Antiviral Immunity in Insects
Cell Reports, 2020 Summary: Transgenerational immune priming (TGIP) allows memory-like immune responses to be transmitted from parents to offspring in many invertebrates.
Juan A. Mondotte +8 more
doaj
RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
, 2009 Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Allison, Simon J., Milner, Jo
core +6 more sources
Molecular mechanisms influencing efficiency of RNA interference in insects.
Pest Management Science, 2018 RNA interference (RNAi) is an endogenous, sequence-specific gene-silencing mechanism elicited by small RNA molecules. RNAi is a powerful reverse genetic tool, and is currently being utilized for managing insects and viruses.
Anastasia M W Cooper +4 more
semanticscholar +1 more source
microRNA Therapeutics in Cancer — An Emerging Concept
EBioMedicine, 2016 MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding RNAs that negatively regulate protein coding gene and other non-coding transcripts expression.
Maitri Y. Shah +4 more
doaj +1 more source
RNA Interference and Small RNA Analysis [PDF]
Cold Spring Harbor Protocols, 2019 Small silencing RNAs have provided powerful reverse genetics tools and have opened new areas of research. This introduction describes the use of RNAi to suppress expression of individual genes for loss-of-function analysis. It also summarizes methods for measuring specific and global changes in small RNA expression, as well as methods to inhibit the ...
Chengjian Li, Phillip D. Zamore
openaire +2 more sources
Frontiers in Plant Science, 2017 Plant reoviruses are able to multiply in gramineae plants and delphacid vectors encountering different defense strategies with unique features. This study aims to comparatively assess alterations of small RNA (sRNA) populations in both hosts upon virus ...
Luis A. de Haro +14 more
doaj +1 more source
Slicing and dicing viruses: antiviral RNA interference in mammals
EMBO Journal, 2019 To protect against the harmful consequences of viral infections, organisms are equipped with sophisticated antiviral mechanisms, including cell‐intrinsic means to restrict viral replication and propagation. Plant and invertebrate cells utilise mostly RNA
P. Maillard +3 more
semanticscholar +1 more source
Random model for RNA interference yields scale free network
, 2003 We introduce a random bit-string model of post-transcriptional genetic regulation based on sequence matching. The model spontaneously yields a scale free network with power law scaling with $ \gamma=-1$ and also exhibits log-periodic behaviour.
Balcan, Duygu, Erzan, Ayse
core +1 more source
P granules protect RNA interference genes from silencing by piRNAs
bioRxiv, 2019 P granules are perinuclear condensates in C. elegans germ cells proposed to serve as hubs for self/non-self RNA discrimination by Argonautes. We report that a mutant (meg-3 meg-4) that does not assemble P granules in primordial germ cells loses ...
J. P. T. Ouyang +7 more
semanticscholar +1 more source
Model-guided design of ligand-regulated RNAi for programmable control of gene expression [PDF]
, 2008 Progress in constructing biological networks will rely on the development of more advanced components that can be predictably modified to yield optimal system performance.
Chase L Beisel +4 more
core +5 more sources