Results 31 to 40 of about 4,574 (248)
Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome. [PDF]
PLoS Genetics, 2015 To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation.
Norishige Yamada +5 more
doaj +1 more source
RNA localization in cytoplasm and nucleus of human embryonic stem cells [PDF]
Jichu yixue yu linchuang, 2020 Objective To investigate the localization of RNA in cytoplasm and nucleus of human embryonic stem cells (hESCs). Methods After separating cytoplasm and nucleus of hESCs, RNAs were extracted for sequencing, and the localization characteristics of RNAs ...
ZHOU Fan-qi, FENG Wen-xin, TAN Pu-wen, MA Yan-ni, WANG Dong, YU Jia
doaj
BMC Genomics, 2021 Background Biological functions of biomolecules rely on the cellular compartments where they are located in cells. Importantly, RNAs are assigned in specific locations of a cell, enabling the cell to implement diverse biochemical processes in the way of ...
Hao Wang +4 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2023 The discovery of several functional interactions where one or even both partners remain disordered has demonstrated that specific interactions do not necessarily require well-defined intermolecular interfaces. Here we describe a fuzzy protein–RNA complex
Deepshikha Verma +3 more
doaj +1 more source
Free circular introns with an unusual branchpoint in neuronal projections
eLife, 2019 The polarized structure of axons and dendrites in neuronal cells depends in part on RNA localization. Previous studies have looked at which polyadenylated RNAs are enriched in neuronal projections or at synapses, but less is known about the distribution ...
Harleen Saini +3 more
doaj +1 more source
RNA Localization Goes Direct [PDF]
Developmental Cell, 2001 Direct injection of RNA provides a new view of localization during Drosophila oogenesis.
Arn, Eric A., Macdonald, Paul M.
openaire +2 more sources
Localisation of RNAs into the germ plasm of vitellogenic xenopus oocytes [PDF]
, 2013 We have studied the localisation of mRNAs in full-grown Xenopus laevis oocytes by injecting fluorescent RNAs, followed by confocal microscopy of the oocyte cortex.
Nijjar, Sarbjit +5 more
core +1 more source
, 2023 International audienceAbstract The localization of RNAs in cells is critical for many cellular processes. Whereas motor‐driven transport of ribonucleoprotein (RNP) condensates plays a prominent role in RNA localization in cells, their study remains ...
Benassy, Marie‐noëlle +11 more
core +1 more source
Novel roles of Celf1 and Tia1 during vegetal RNA localization in Xenopus laevis oocytes [PDF]
, 2015 The localization of certain mRNAs to the vegetal cortex of Xenopus oocytes is of crucial importance for germ cell development and germ layer formation of the future embryo. Vegetal RNA localization is mediated by signal sequences within the RNA. These so-
Bauermeister, Diana
core +1 more source
An essential role for maternal control of Nodal signaling
eLife, 2013 Growth factor signaling is essential for pattern formation, growth, differentiation, and maintenance of stem cell pluripotency. Nodal-related signaling factors are required for axis formation and germ layer specification from sea urchins to mammals ...
Pooja Kumari +6 more
doaj +1 more source