Intron and Small RNA Localization in Mammalian Neurons [PDF]
, 2019 RNA molecules are diverse in form and function. They include messenger RNAs (mRNAs) that are templates for proteins, splice products such as introns that can generate functional noncoding RNAs, and a slew of smaller RNAs such as transfer RNAs (tRNAs ...
Saini, Harleen
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RNA localization in cytoplasm and nucleus of human embryonic stem cells [PDF]
Jichu yixue yu linchuang, 2020 Objective To investigate the localization of RNA in cytoplasm and nucleus of human embryonic stem cells (hESCs). Methods After separating cytoplasm and nucleus of hESCs, RNAs were extracted for sequencing, and the localization characteristics of RNAs ...
ZHOU Fan-qi, FENG Wen-xin, TAN Pu-wen, MA Yan-ni, WANG Dong, YU Jia
doaj
Importin-α-mediated nucleolar localization of potato mop-top virus TRIPLE GENE BLOCK1 (TGB1) protein facilitates virus systemic movement, whereas TGB1 self-interaction is required for cell-to-cell movement in Nicotiana benthamiana [PDF]
, 2015 This work was supported by the Swedish Research Council Formas (to E.I.S.), the Carl Tryggers Foundation (to E.I.S. and N.I.L.), the Swedish Institute (to N.I.L.), and the Rural and Environmental Science and Analytical Services Division strategic ...
Savenkov, Eugene I. +5 more
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Free circular introns with an unusual branchpoint in neuronal projections
eLife, 2019 The polarized structure of axons and dendrites in neuronal cells depends in part on RNA localization. Previous studies have looked at which polyadenylated RNAs are enriched in neuronal projections or at synapses, but less is known about the distribution ...
Harleen Saini +3 more
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Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome. [PDF]
PLoS Genetics, 2015 To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation.
Norishige Yamada +5 more
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Frontiers in Molecular Biosciences, 2023 The discovery of several functional interactions where one or even both partners remain disordered has demonstrated that specific interactions do not necessarily require well-defined intermolecular interfaces. Here we describe a fuzzy protein–RNA complex
Deepshikha Verma +3 more
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In vivo Imaging of oskar mRNA transport reveals the mechanism of posterior localization [PDF]
, 2008 oskar mRNA localization to the posterior of the Drosophila oocyte defines where the abdomen and germ cells form in the embryo. Although this localization requires microtubules and the plus end-directed motor, kinesin, its mechanism is controversial and ...
Zimyanin, Vitaly L +16 more
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An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]
, 2013 Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354) +29 more
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Localisation of RNAs into the germ plasm of vitellogenic xenopus oocytes [PDF]
, 2013 We have studied the localisation of mRNAs in full-grown Xenopus laevis oocytes by injecting fluorescent RNAs, followed by confocal microscopy of the oocyte cortex.
Nijjar, Sarbjit +5 more
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Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Richard M. Elliott +16 more
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