Results 1 to 10 of about 3,365,264 (261)
Impact of Nuclear Export Pathway on Cytoplasmic HIV-1 RNA Transport Mechanism and Distribution [PDF]
mBio, 2020 HIV-1 full-length RNA (referred to as HIV-1 RNA here) serves as the viral genome in virions and as a template for Gag/Gag-Pol translation. We previously showed that HIV-1 RNA, which is exported via the CRM1 pathway, travels in the cytoplasm mainly ...
Jianbo Chen +7 more
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Directional transport is mediated by a Dynein-dependent step in an RNA localization pathway. [PDF]
PLoS Biology, 2013 Cytoplasmic RNA localization is a key biological strategy for establishing polarity in a variety of organisms and cell types. However, the mechanisms that control directionality during asymmetric RNA transport are not yet clear. To gain insight into this
James A Gagnon +4 more
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Microtubule-based transport is essential to distribute RNA and nascent protein in skeletal muscle
Nature Communications, 2021 It is increasingly recognised that the spatial localisation of RNA is important for proper cellular function. Here, the authors investigate RNA localisation in skeletal muscle and develop methods to show that global active transport of RNA is required to
Lance T. Denes +2 more
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Role of RNA Biogenesis Factors in the Processing and Transport of Human Telomerase RNA
Biomedicines, 2022 Telomerase RNA has long been considered to be a noncoding component of telomerase. However, the expression of the telomerase RNA gene is not always associated with telomerase activity.
Tatiana Pakhomova +5 more
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RNA Motifs and Modification Involve in RNA Long-Distance Transport in Plants
Frontiers in Cell and Developmental Biology, 2021 A large number of RNA molecules have been found in the phloem of higher plants, and they can be transported to distant organelles through the phloem.
Tao Wang +10 more
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PLoS Pathogens, 2023 Aichi virus (AiV), a small non-enveloped RNA virus, hijacks the endoplasmic reticulum (ER)-Golgi cholesterol transport machinery to form cholesterol-rich replication sites originating from Golgi membranes.
Kumiko Ishikawa-Sasaki +2 more
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Unidirectional P-body transport during the yeast cell cycle. [PDF]
PLoS ONE, 2014 P-bodies belong to a large family of RNA granules that are associated with post-transcriptional gene regulation, conserved from yeast to mammals, and influence biological processes ranging from germ cell development to neuronal plasticity.
Cecilia Garmendia-Torres +9 more
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Communications Biology, 2021 Okabe et al. show that the miRNA production system in the neuron and the small RNA transport machinery in the intestine are required for the acquisition of hormesis.
Emiko Okabe +3 more
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RNA transport during TMV cell-to-cell movement
Frontiers in Plant Science, 2012 Studies during the last twenty-five years have provided increasing evidence for the ability of plants to support the cell-to-cell and systemic transport of RNA molecules and that this process plays a role in plant development and in the systemic ...
Eduardo José ePeña +2 more
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Frontiers in Cell and Developmental Biology, 2022 Mutations in TDP-43, a RNA-binding protein with multiple functions in RNA metabolism, cause amyotrophic lateral sclerosis (ALS), but it is uncertain how defects in RNA biology trigger motor neuron degeneration.
Sonali S. Vishal +4 more
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