The nucleolus is the most prominent subnuclear compartment in eukaryotic cells. It has a central function in the biogenesis of ribosomal subunits, but the past decade has revealed that a variety of additional non-ribosomal ribonucleoprotein (RNP ...
Jellbauer, Stephan
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An essential role for maternal control of Nodal signaling
Growth factor signaling is essential for pattern formation, growth, differentiation, and maintenance of stem cell pluripotency. Nodal-related signaling factors are required for axis formation and germ layer specification from sea urchins to mammals ...
Pooja Kumari +6 more
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Mechanical Fractionation of Cultured Neuronal Cells into Cell Body and Neurite Fractions
Many cells contain spatially defined subcellular regions that perform specialized tasks enabled by localized proteins. The subcellular distribution of these localized proteins is often facilitated by the subcellular localization of the RNA molecules that
Ankita Arora +3 more
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RNA Localization Goes Direct [PDF]
Direct injection of RNA provides a new view of localization during Drosophila oogenesis.
Arn, Eric A., Macdonald, Paul M.
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Techniques for RNA in vivo imaging in plants [PDF]
Since the discovery of small RNAs and RNA silencing, RNA biology has taken a centre stage in cell and developmental biology. Small RNAs, but also mRNAs and other types of cellular and viral RNAs are processed at specific subcellular localizations.
Tilsner, Jens
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In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles [PDF]
The NHPX protein is a nucleolar factor that binds directly to a conserved RNA target sequence found in nucleolar box C/D snoRNAs and in U4 snRNA. Using enhanced yellow fluorescent protein (EYFP)– and enhanced cyan fluorescent protein–NHPX fusions, we ...
Leung, Anthony K. L. +3 more
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Characterizing functional domains of the RNA helicase RHAU involved in subcellular localization and RNA interaction [PDF]
Posttranscriptional regulation of gene expression is an important and highly regulated process in response to developmental, environmental and metabolic signals.
Chalupníková, Katerina
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Axon micro-dissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons [PDF]
Axonal protein synthesis has been shown to play a role in developmental and regenerative growth, as well as in the maintenance of the axoplasm in steady state.
Sotelo-Silveira, José Roberto +3 more
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RNA Locally Optimal Secondary Structures [PDF]
RNA locally optimal secondary structures provide a concise and exhaustive description of all possible secondary structures of a given RNA sequence, and hence a very good representation of the RNA folding space. In this paper, we present an efficient algorithm that computes all locally optimal secondary structures for any folding model that takes into ...
Saffarian, Azadeh +3 more
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Coalescence of the sites of cowpea mosaic virus RNA replication into a cytopathic structure [PDF]
Cowpea mosaic virus (CPMV) replication induces an extensive proliferation of endoplasmic reticulum (ER) membranes, leading to the formation of small membranous vesicles where viral RNA replication takes place.
Carette, J.E. +3 more
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