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Prediction of RNA subcellular localization: Learning from heterogeneous data sources
iScience, 2021 Summary: RNA subcellular localization has recently emerged as a widespread phenomenon, which may apply to the majority of RNAs. The two main sources of data for characterization of RNA localization are sequence features and microscopy images, such as ...
Anca Flavia Savulescu +3 more
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Computational and Structural Biotechnology Journal, 2022 Subcellular localization of Ribonucleic Acid (RNA) molecules provide significant insights into the functionality of RNAs and helps to explore their association with various diseases.
Muhammad Nabeel Asim +7 more
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RNA localization in bacteria [PDF]
RNA Biology, 2014 One of the most important discoveries in the field of microbiology in the last two decades is that bacterial cells have intricate subcellular organization. This understanding has emerged mainly from the depiction of spatial and temporal organization of proteins in specific domains within bacterial cells, e.g., midcell, cell poles, membrane and ...
Avi-ad Avraam, Buskila +2 more
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
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Quantitative analysis of subcellular distributions with an open-source, object-based tool
Biology Open, 2020 The subcellular localization of objects, such as organelles, proteins, or other molecules, instructs cellular form and function. Understanding the underlying spatial relationships between objects through colocalization analysis of microscopy images is a ...
Pearl V. Ryder, Dorothy A. Lerit
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iScience, 2022 Summary: RNA localization and biomolecular condensate formation are key biological strategies for organizing the cytoplasm and generating cellular polarity. In Xenopus oocytes, RNAs required for germ layer patterning localize in biomolecular condensates,
Sarah E. Cabral +2 more
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RNA localization regulates diverse and dynamic cellular processes [PDF]
Traffic, 2018 Dorothy A Lerit, Pearl V Ryder
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Localization of RNA and translation in the mammalian oocyte and embryo. [PDF]
PLoS ONE, 2018 The tight correlation between mRNA distribution and subsequent protein localization and function indicate a major role for mRNA localization within the cell.
Denisa Jansova +4 more
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The EMBO Reports, 2007 Figure 1. The first joint EMBO/FASEB Workshop on Intracellular RNA Localization and Localized Translation took place between 1 and 6 July 2007, in Il Ciocco, Italy, and was organized by A. Ephrussi, E. Gavis, D. Ish‐Horowicz and J. Richter. Originally a biannual FASEB summer research conference, it is anticipated that the joint meeting will in future
Patrick C, Gilligan, Karuna, Sampath
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RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +3 more
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