A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. [PDF]
PLoS Biology, 2011 In eukaryotes, hundreds of mRNAs are localized by specialized transport complexes. For localization, transcripts are recognized by RNA-binding proteins and incorporated into motor-containing messenger ribonucleoprotein particles (mRNPs).
Marisa Müller +8 more
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Protein localization with flexible DNA or RNA. [PDF]
PLoS ONE, 2012 Localization of activity is ubiquitous in life, and also within sub-cellular compartments. Localization provides potential advantages as different proteins involved in the same cellular process may supplement each other on a fast timescale. It might also
Sebastian Bernhardsson +2 more
doaj +5 more sources
A computational framework to study sub-cellular RNA localization [PDF]
Nature Communications, 2018 Automated analysis of RNA localisation in smFISH data has been elusive. Here, the authors simulate and use a large dataset of images to design and validate a framework for highly accurate classification of sub-cellular RNA localisation patterns from ...
Aubin Samacoits +9 more
doaj +2 more sources
Editorial: RNA Localization and Localized Translation in Neurons. [PDF]
Front Integr Neurosci, 2021 Published ...
Farris S +3 more
europepmc +5 more sources
Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER [PDF]
Cell Reports, 2022 Romana A. Nowak, Jing Yang, Taejoon Kwon
exaly +2 more sources
A review from biological mapping to computation-based subcellular localization
Molecular Therapy: Nucleic Acids, 2023 Subcellular localization is crucial to the study of virus and diseases. Specifically, research on protein subcellular localization can help identify clues between virus and host cells that can aid in the design of targeted drugs.
Jing Li, Quan Zou, Lei Yuan
doaj +1 more source
RNA localization and co‐translational interactions control RAB13 GTPase function and cell migration [PDF]
EMBO Journal, 2020 Konstadinos Moissoglu +2 more
exaly +2 more sources
RNA Localization in Bacteria. [PDF]
Microbiol Spectr, 2018 ABSTRACT Diverse mechanisms and functions of posttranscriptional regulation by small regulatory RNAs and RNA-binding proteins have been described in bacteria. In contrast, little is known about the spatial organization of RNAs in bacterial cells.
Fei J, Sharma CM.
europepmc +4 more sources
Meiotic long non-coding meiRNA accumulates as a dot at its genetic locus facilitated by Mmi1 and plays as a decoy to lure Mmi1 [PDF]
Open Biology, 2014 Long non-coding RNAs (lncRNAs) play key roles in the formation of nuclear bodies. In the fission yeast Schizosaccharomyces pombe, a lncRNA species termed meiRNA forms a nuclear dot structure at its own genetic locus, the sme2 locus, with its protein ...
Yuichi Shichino +2 more
doaj +1 more source
RNA LOCALIZATION IN DEVELOPMENT [PDF]
Annual Review of Biochemistry, 1998 Cytoplasmic RNA localization is an evolutionarily ancient mechanism for producing cellular asymmetries. This review considers RNA localization in the context of animal development. Both mRNAs and non-protein-coding RNAs are localized in Drosophila, Xenopus, ascidian, zebrafish, and echinoderm oocytes and embryos, as well as in a variety of developing ...
Bashirullah, Arash +2 more
openaire +3 more sources