Results 201 to 210 of about 250,698 (260)

Comprehensive analysis of m6A RNA methylation regulators for prognostic risk stratification and immune microenvironment characterization in colorectal cancer. [PDF]

Open Med (Wars)
Kong FF, Feng J, Liu JY, Gan WY, Zhu LJ.
europepmc   +1 more source

An Enzymatic Platform for Late‐Stage (Radio)isotope Labelling of Oligonucleotides With Methyltransferases

Angewandte Chemie, EarlyView.
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson, Ulrich Kauhl, Martin R. Edelmann, Florian P. Seebeck   +3 more
wiley   +1 more source

Unlocking the potential: m6A-RNA methylation in severe epidermolysis bullosa simplex. [PDF]

Biosci Rep
Balacco DL, Hewitt BJ, Bardhan A, Shriane LM, Hunjan M, Hickerson R, Heagerty AHM, Chapple IL.   +7 more
europepmc   +1 more source

Proteome‐Wide Target Identification Using Reactive Metallo‐Scaffolds (r‐mS): A Platform for Metallodrug Discovery

Angewandte Chemie, EarlyView.
Re‐envisioning the Ligandable Proteome: Reactive Metallo‐Scaffolds (r‐mS) combine non‐covalent protein engagement by a metallo‐scaffold with covalent cysteine capture through a tethered chloroacetamide warhead. Chemoproteomic profiling reveals unique enzyme engagement including ligases, kinases and methyltransferases, highlighting opportunities for ...
Jessica E. Waters, Harry Wilders, George S. Biggs, Mika Kintzel, Emma E. Cawood, Jonathan Bailey, Sarah Maslen, Yew Mun Yip, Mason Wakley, Ioannis G. Riziotis, Thomas W. Rees, Joanna Redmond, J. Mark Skehel, David House, Jacob Bush, Jeannine Hess   +15 more
wiley   +1 more source

Genetic characteristics and prognosis of m6A RNA methylation regulator in acute myeloid leukemia. [PDF]

Genes Dis
Liao K, Guo D, Hu Y, Wen J, Xu Y, Bai X, Cheng J, Zhang B, Wang X.   +8 more
europepmc   +1 more source

Neuromodulatory role and therapeutic potential of N 6 -methyladenosine RNA methylation in neurodegenerative diseases. [PDF]

Neural Regen Res
Zhang J, Ma W, Liu R, Li X, Yuan Z, Cheng J.   +5 more
europepmc   +1 more source

METTL3-dependent m6A RNA methylation suppresses aberrant mammary epithelial differentiation and neoplastic transformation. [PDF]

Proc Natl Acad Sci U S A
Li Y, Qiu X, Sandusky Z, Tagliaferri K, Li R, Yang X, Zhang T, Liu S, Yan P, Lu F, Jones M, Xiao T, Li W, Goldman S, Cui J, Polyak K, Liu XS, Long HW, Gregory RI, Adelman K, Rosenbluth JM, Brown M.   +21 more
europepmc   +1 more source

DNA and RNA Methylation in Rheumatoid Arthritis-A Narrative Review. [PDF]

Epigenomes
Kiełbowski K, Bakinowska E, Gorący-Rosik A, Figiel K, Judek R, Rosik J, Dec P, Modrzejewski A, Pawlik A.   +8 more
europepmc   +1 more source

m5C RNA methylation in cancer: from biological mechanism to clinical perspectives. [PDF]

Eur J Med Res
Yuan F, Xia Y, Huang Z, Gao H, Bian Y, Zhou X.   +5 more
europepmc   +1 more source

Statement of Retraction: Ibuprofen promotes p75 neurotrophin receptor expression through modifying promoter methylation and N6-methyladenosine-RNA-methylation in human gastric cancer cells. [PDF]

Bioengineered
europepmc   +1 more source