Results 221 to 230 of about 250,698 (260)
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Mitochondrial RNA methylation in cancer
Biochimica et Biophysica Acta (BBA) - Reviews on CancerMitochondria have a complete and independent genetic system with necessary biological energy for cancer occurrence and persistence. Mitochondrial RNA (mt-RNA) methylation, as a frontier in epigenetics, has linked to cancer progression with growing evidences.
Luyi, Tan +6 more
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When RNA methylation meets DNA methylation
Nature Genetics, 2022Wenqi Xu, Hongjie Shen
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Methylation of Mouse Ribosomal RNA Genes
DNA, 1982Ribosomal DNA (rDNA) methylation was studied in various strains of mice. We used restriction enzymes that are sensitive to methylation and a cloned probe containing the transcribed spacer and part of the 18S and 28S gene. Strains C3H/He3, C57/B6-3, and AKR/J were found to have less than 9% of the rDNA methylated.
J G, Reilly, C A, Thomas, M J, Lundell
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Methylation of rat-liver RNA in vivo by methyl methanesulphonate
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969Abstract The time-course of methylation of rat-liver RNA in vivo was determined following intraperitoneal injection of a single dose (50–57 mg/kg body weight) of [14C]methyl methanesulphonate. The purified RNA was subjected to acid hydrolysis and the products were separated by ion-exchange chromatography.
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RNA-directed DNA methylation in plants
Plant Cell Reports, 2015In plants, many small interfering RNAs (siRNAs) direct de novo methylation by DNA methyltransferase. DNA methylation typically occurs by RNA-directed DNA methylation (RdDM), which directs transcriptional gene silencing of transposons and endogenous transgenes. RdDM is driven by non-coding RNAs (ncRNAs) produced by DNA-dependent RNA polymerases IV and V
Ali, Movahedi +7 more
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Studies on the biosynthesis and methylation of transfer RNA
Journal of Molecular Biology, 1964A rapidly labeled RNA fraction of the nucleolus has been isolated and partially characterized. This RNA component appears to be a precursor of transfer RNA. It contains neither pseudouridine nor methylated bases, and is unable to form amino acyl RNA. However, it resembles transfer RNA in base composition and molecular weight.
D G, COMB, S, KATZ
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Trends in Biochemical Sciences, 1976
Abstract Eukaryotic messenger RNA molecules contain methylated nucleotides, both at their 5′-terminal end in a unique ‘cap' structure, and internally as 6-methyladenylic acid. Similar methylation patterns are.found in heterogeneous nuclear RNA molecules.
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Abstract Eukaryotic messenger RNA molecules contain methylated nucleotides, both at their 5′-terminal end in a unique ‘cap' structure, and internally as 6-methyladenylic acid. Similar methylation patterns are.found in heterogeneous nuclear RNA molecules.
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RNA m6A methylation at the juxtaposition of apoptosis and RNA therapeutics
Trends in Cell BiologyTargeting RNA m6A marks in apoptosis-related transcripts holds promise for RNA therapeutics. However, pathway-specific RNA m6A sites on pro- or antiapoptotic transcripts have not been fully unveiled, let alone characterized. This article summarizes the current knowledge and gaps in the cellular response modulated by apoptotic stimulus-specific RNA m6A ...
Bünyamin Akgül +2 more
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Small Nucleolar RNAs Guide Ribosomal RNA Methylation
Science, 1996Two recent reports, one in Cell and one in the Journal of Molecular Biology , show that the newly described small nucleolar RNAs control the site of methylation of the ribosomal RNA (rRNA). Tollervey explains how these small RNAs accomplish this targeting and discusses the possible role of ...
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The methylation of transfer RNA by methyl cobamide
Biochemical and Biophysical Research Communications, 1966W S, Walerych +2 more
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